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Research Article

Genome-Wide Copy Number Variation in Epilepsy: Novel Susceptibility Loci in Idiopathic Generalized and Focal Epilepsies

  • Heather C. Mefford mail,

    hmefford@u.washington.edu

    Affiliations: Department of Pediatrics, University of Washington, Seattle, Washington, United States of America, Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America

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  • Hiltrud Muhle,

    Affiliation: Department of Neuropediatrics, Christian-Albrechts University of Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany

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  • Philipp Ostertag,

    Affiliation: Department of Neuropediatrics, Christian-Albrechts University of Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany

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  • Sarah von Spiczak,

    Affiliation: Department of Neuropediatrics, Christian-Albrechts University of Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany

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  • Karen Buysse,

    Affiliation: Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium

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  • Carl Baker,

    Affiliation: Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America

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  • Andre Franke,

    Affiliation: Institute of Clinical Molecular Biology, Christian-Albrechts University, Kiel, Germany

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  • Alain Malafosse,

    Affiliation: Department of Genetic Medicine and Development, University of Geneva Medical School and University Hospitals of Geneva, Geneva, Switzerland

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  • Pierre Genton,

    Affiliation: Centre Saint Paul-Hôpital Henri Gastaut, Marseilles, France

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  • Pierre Thomas,

    Affiliation: Unité Fonctionnelle EEG-Epileptologie and Service de Neurologie, Hôpital Pasteur, Nice, France

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  • Christina A. Gurnett,

    Affiliation: Department of Neurology, Washington University, St. Louis, Missouri, United States of America

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  • Stefan Schreiber,

    Affiliation: Institute of Clinical Molecular Biology, Christian-Albrechts University, Kiel, Germany

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  • Alexander G. Bassuk,

    Affiliation: Department of Pediatrics, University of Iowa, Iowa City, Iowa, United States of America

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  • Michel Guipponi,

    Affiliation: Department of Genetic Medicine and Development, University of Geneva Medical School and University Hospitals of Geneva, Geneva, Switzerland

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  • Ulrich Stephani,

    Affiliation: Department of Neuropediatrics, Christian-Albrechts University of Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany

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  • Ingo Helbig,

    Affiliation: Department of Neuropediatrics, Christian-Albrechts University of Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany

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  • Evan E. Eichler

    Affiliations: Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America, Howard Hughes Medical Institute, University of Washington, Seattle, Washington, United States of America

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  • Published: May 20, 2010
  • DOI: 10.1371/journal.pgen.1000962

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