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Research Article

Common Genetic Variants near the Brittle Cornea Syndrome Locus ZNF469 Influence the Blinding Disease Risk Factor Central Corneal Thickness

  • Yi Lu equal contributor,

    equal contributor Contributed equally to this work with: Yi Lu, David P. Dimasi

    Affiliation: Genetics and Population Health, Queensland Institute of Medical Research, Brisbane, Australia

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  • David P. Dimasi equal contributor,

    equal contributor Contributed equally to this work with: Yi Lu, David P. Dimasi

    Affiliation: Department of Ophthalmology, Flinders University, Adelaide, Australia

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  • Pirro G. Hysi,

    Affiliation: Department of Twin Research and Genetic Epidemiology, King's College London School of Medicine, St Thomas' Hospital, London, United Kingdom

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  • Alex W. Hewitt,

    Affiliation: Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Australia

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  • Kathryn P. Burdon,

    Affiliation: Department of Ophthalmology, Flinders University, Adelaide, Australia

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  • Tze'Yo Toh,

    Affiliations: Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Australia, University of Tasmania, the Eye Hospital, Launceston, Australia

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  • Jonathan B. Ruddle,

    Affiliation: Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Australia

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  • Yi Ju Li,

    Affiliations: Center for Human Genetics, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, North Carolina, United States of America

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  • Paul Mitchell,

    Affiliation: Centre for Vision Research, Westmead Millennium Institute, University of Sydney, Sydney, Australia

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  • Paul R. Healey,

    Affiliation: Centre for Vision Research, Westmead Millennium Institute, University of Sydney, Sydney, Australia

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  • Grant W. Montgomery,

    Affiliation: Genetics and Population Health, Queensland Institute of Medical Research, Brisbane, Australia

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  • Narelle Hansell,

    Affiliation: Genetics and Population Health, Queensland Institute of Medical Research, Brisbane, Australia

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  • Timothy D. Spector,

    Affiliation: Department of Twin Research and Genetic Epidemiology, King's College London School of Medicine, St Thomas' Hospital, London, United Kingdom

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  • Nicholas G. Martin,

    Affiliation: Genetics and Population Health, Queensland Institute of Medical Research, Brisbane, Australia

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  • Terri L. Young,

    Affiliation: Center for Human Genetics, Duke University Medical Center, Durham, North Carolina, United States of America

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  • Christopher J. Hammond,

    Affiliation: Department of Twin Research and Genetic Epidemiology, King's College London School of Medicine, St Thomas' Hospital, London, United Kingdom

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  • Stuart Macgregor ,

    Affiliation: Genetics and Population Health, Queensland Institute of Medical Research, Brisbane, Australia

    These authors also contributed equally to this work.

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  • Jamie E. Craig mail,

    jamie.craig@flinders.edu.au

    Affiliation: Department of Ophthalmology, Flinders University, Adelaide, Australia

    These authors also contributed equally to this work.

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  • David A. Mackey

    Affiliations: Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Australia, Lions Eye Institute, University of Western Australia, Centre for Ophthalmology and Visual Science, Perth, Australia

    These authors also contributed equally to this work.

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  • Published: May 13, 2010
  • DOI: 10.1371/journal.pgen.1000947

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