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Research Article

The Caenorhabditis elegans Werner Syndrome Protein Functions Upstream of ATR and ATM in Response to DNA Replication Inhibition and Double-Strand DNA Breaks

  • Se-Jin Lee,

    Affiliation: Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea

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  • Anton Gartner,

    Affiliation: Wellcome Trust Centre for Gene Regulation and Expression, School of Life Sciences, The University of Dundee, Dundee, United Kingdom

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  • Moonjung Hyun,

    Affiliation: Department of Life Sciences, University of Ulsan, Ulsan, Korea

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  • Byungchan Ahn,

    Affiliation: Department of Life Sciences, University of Ulsan, Ulsan, Korea

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  • Hyeon-Sook Koo mail

    kooh@yonsei.ac.kr.

    Affiliation: Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea

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  • Published: January 08, 2010
  • DOI: 10.1371/journal.pgen.1000801

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