Advertisement
Research Article

Frequent Long-Range Epigenetic Silencing of Protocadherin Gene Clusters on Chromosome 5q31 in Wilms' Tumor

  • Anthony R. Dallosso,

    Affiliation: Cancer and Leukaemia in Childhood – Sargent Research Unit, Department of Cellular and Molecular Medicine, School of Medical Sciences, University of Bristol, Bristol, United Kingdom

    X
  • Anne L. Hancock,

    Affiliation: Cancer and Leukaemia in Childhood – Sargent Research Unit, Department of Cellular and Molecular Medicine, School of Medical Sciences, University of Bristol, Bristol, United Kingdom

    X
  • Marianna Szemes,

    Affiliation: Cancer and Leukaemia in Childhood – Sargent Research Unit, Department of Cellular and Molecular Medicine, School of Medical Sciences, University of Bristol, Bristol, United Kingdom

    X
  • Kim Moorwood,

    Affiliation: Department of Biology and Biochemistry, University of Bath, Bath, United Kingdom

    X
  • Laxmi Chilukamarri,

    Affiliation: Cancer and Leukaemia in Childhood – Sargent Research Unit, Department of Cellular and Molecular Medicine, School of Medical Sciences, University of Bristol, Bristol, United Kingdom

    X
  • Hsin-Hao Tsai,

    Affiliation: Cancer and Leukaemia in Childhood – Sargent Research Unit, Department of Cellular and Molecular Medicine, School of Medical Sciences, University of Bristol, Bristol, United Kingdom

    X
  • Abby Sarkar,

    Affiliation: Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, United States of America

    X
  • Jonathan Barasch,

    Affiliation: Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, United States of America

    X
  • Raisa Vuononvirta,

    Affiliation: Paediatric Oncology, Institute of Cancer Research/Royal Marsden NHS Trust, Sutton, United Kingdom

    X
  • Chris Jones,

    Affiliation: Paediatric Oncology, Institute of Cancer Research/Royal Marsden NHS Trust, Sutton, United Kingdom

    X
  • Kathy Pritchard-Jones,

    Affiliation: Paediatric Oncology, Institute of Cancer Research/Royal Marsden NHS Trust, Sutton, United Kingdom

    X
  • Brigitte Royer-Pokora,

    Affiliation: Institute of Human Genetics and Anthropology, Heinrich-Heine University of Duesseldorf, Duesseldorf, Germany

    X
  • Sean Bong Lee,

    Affiliation: Genetics of Development and Disease Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Ceris Owen,

    Affiliation: Cancer and Leukaemia in Childhood – Sargent Research Unit, Department of Cellular and Molecular Medicine, School of Medical Sciences, University of Bristol, Bristol, United Kingdom

    X
  • Sally Malik,

    Affiliation: Cancer and Leukaemia in Childhood – Sargent Research Unit, Department of Cellular and Molecular Medicine, School of Medical Sciences, University of Bristol, Bristol, United Kingdom

    X
  • Yi Feng,

    Affiliation: Department of Biochemistry, School of Medical Sciences, University of Bristol, Bristol, United Kingdom

    X
  • Marcus Frank,

    Affiliation: Developmental Biology, Institute of Biology 1, University of Freiburg, Freiburg, Germany

    X
  • Andrew Ward,

    Affiliation: Department of Biology and Biochemistry, University of Bath, Bath, United Kingdom

    X
  • Keith W. Brown mail,

    Keith.Brown@bristol.ac.uk (KWB); k.t.a.malik@bristol.ac.uk (KM)

    Affiliation: Cancer and Leukaemia in Childhood – Sargent Research Unit, Department of Cellular and Molecular Medicine, School of Medical Sciences, University of Bristol, Bristol, United Kingdom

    X
  • Karim Malik mail

    Keith.Brown@bristol.ac.uk (KWB); k.t.a.malik@bristol.ac.uk (KM)

    Affiliation: Cancer and Leukaemia in Childhood – Sargent Research Unit, Department of Cellular and Molecular Medicine, School of Medical Sciences, University of Bristol, Bristol, United Kingdom

    X
  • Published: November 26, 2009
  • DOI: 10.1371/journal.pgen.1000745

Reader Comments (0)

Post a new comment on this article