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Research Article

Loss of Yeast Peroxiredoxin Tsa1p Induces Genome Instability through Activation of the DNA Damage Checkpoint and Elevation of dNTP Levels

  • Hei-Man Vincent Tang,

    Affiliation: Department of Biochemistry, The University of Hong Kong, Pokfulam, Hong Kong, Special Administrative Region, People's Republic of China

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  • Kam-Leung Siu,

    Affiliation: Department of Biochemistry, The University of Hong Kong, Pokfulam, Hong Kong, Special Administrative Region, People's Republic of China

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  • Chi-Ming Wong mail,

    wispwong@hkucc.hku.hk (C-MW); dyjin@hkucc.hku.hk (D-YJ)

    Affiliation: Department of Biochemistry, The University of Hong Kong, Pokfulam, Hong Kong, Special Administrative Region, People's Republic of China

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  • Dong-Yan Jin mail

    wispwong@hkucc.hku.hk (C-MW); dyjin@hkucc.hku.hk (D-YJ)

    Affiliation: Department of Biochemistry, The University of Hong Kong, Pokfulam, Hong Kong, Special Administrative Region, People's Republic of China

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  • Published: October 23, 2009
  • DOI: 10.1371/journal.pgen.1000697

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