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Research Article

From Disease Association to Risk Assessment: An Optimistic View from Genome-Wide Association Studies on Type 1 Diabetes

  • Zhi Wei equal contributor,

    equal contributor Contributed equally to this work with: Zhi Wei, Kai Wang

    Affiliation: Department of Computer Science, New Jersey Institute of Technology, Newark, New Jersey, United States of America

    X
  • Kai Wang equal contributor,

    equal contributor Contributed equally to this work with: Zhi Wei, Kai Wang

    Affiliation: Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

    X
  • Hui-Qi Qu,

    Affiliation: Departments of Pediatrics and Human Genetics, McGill University, Montreal, Québec, Canada

    X
  • Haitao Zhang,

    Affiliation: Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

    X
  • Jonathan Bradfield,

    Affiliation: Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

    X
  • Cecilia Kim,

    Affiliation: Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

    X
  • Edward Frackleton,

    Affiliation: Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

    X
  • Cuiping Hou,

    Affiliation: Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

    X
  • Joseph T. Glessner,

    Affiliation: Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

    X
  • Rosetta Chiavacci,

    Affiliation: Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

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  • Charles Stanley,

    Affiliation: Division of Endocrinology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

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  • Dimitri Monos,

    Affiliation: Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

    X
  • Struan F. A. Grant,

    Affiliations: Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America, Division of Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

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  • Constantin Polychronakos,

    Affiliation: Departments of Pediatrics and Human Genetics, McGill University, Montreal, Québec, Canada

    X
  • Hakon Hakonarson mail

    hakonarson@chop.edu

    Affiliations: Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America, Division of Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

    X
  • Published: October 09, 2009
  • DOI: 10.1371/journal.pgen.1000678

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