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Research Article

Mitochondrial Targeting Adaptation of the Hominoid-Specific Glutamate Dehydrogenase Driven by Positive Darwinian Selection

  • Lia Rosso,

    Affiliation: Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland

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  • Ana C. Marques,

    Affiliation: Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland

    Current address: MRC Functional Genomics Unit (FGU), Department of Human Anatomy and Genetics, Oxford, United Kingdom

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  • Andreas S. Reichert,

    Affiliation: Cluster of Excellence “Macromolecular Complexes”, Mitochondriale Biologie, Fachbereich Medizin, Johann Wolfgang Goethe–Universität Frankfurt am Main, Frankfurt am Main, Germany

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  • Henrik Kaessmann mail

    henrik.kaessmann@unil.ch

    Affiliation: Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland

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  • Published: August 08, 2008
  • DOI: 10.1371/journal.pgen.1000150

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