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Research Article

Genome-Wide Association Identifies a Common Variant in the Reelin Gene That Increases the Risk of Schizophrenia Only in Women

  • Sagiv Shifman mail,

    To whom correspondence should be addressed. E-mail: sagiv@vms.huji.ac.il

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kindgdom

    ¤ Current address: Department of Genetics, The Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel

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  • Martina Johannesson,

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kindgdom

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  • Michal Bronstein,

    Affiliation: Department of Genetics, The Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel

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  • Sam X Chen,

    Affiliations: Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia, United States of America, Virginia Institute for Psychiatric and Behavior Genetics, Virginia Commonwealth University, Richmond, Virginia, United States of America

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  • David A Collier,

    Affiliation: Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, London, United Kingdom

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  • Nicholas J Craddock,

    Affiliation: Department of Psychological Medicine, School of Medicine, Cardiff University, Cardiff, United Kingdom

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  • Kenneth S Kendler,

    Affiliations: Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia, United States of America, Virginia Institute for Psychiatric and Behavior Genetics, Virginia Commonwealth University, Richmond, Virginia, United States of America

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  • Tao Li,

    Affiliations: Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, London, United Kingdom, Psychiatric Laboratory and Department of Psychiatry, West China Hospital, Sichuan University, The People's Republic of China, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, The People's Republic of China

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  • Michael O'Donovan,

    Affiliation: Department of Psychological Medicine, School of Medicine, Cardiff University, Cardiff, United Kingdom

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  • F. Anthony O'Neill,

    Affiliation: The Department of Psychiatry, The Queens University, Belfast, Northern Ireland

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  • Michael J Owen,

    Affiliation: Department of Psychological Medicine, School of Medicine, Cardiff University, Cardiff, United Kingdom

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  • Dermot Walsh,

    Affiliation: The Health Research Board, Dublin, Ireland

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  • Daniel R Weinberger,

    Affiliation: Clinical Brain Disorders Branch, Genes, Cognition, and Psychosis Program, Intramural Research Program, National Institute of Mental Health, National Institutes of Health (NIH), United States Department of Health and Human Services, Bethesda, Maryland, United States of America

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  • Cuie Sun,

    Affiliations: Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia, United States of America, Virginia Institute for Psychiatric and Behavior Genetics, Virginia Commonwealth University, Richmond, Virginia, United States of America

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  • Jonathan Flint,

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kindgdom

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  • Ariel Darvasi

    Affiliation: Department of Genetics, The Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel

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  • Published: February 15, 2008
  • DOI: 10.1371/journal.pgen.0040028

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