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Research Article

A Screen for Suppressors of Gross Chromosomal Rearrangements Identifies a Conserved Role for PLP in Preventing DNA Lesions

  • Pamela Kanellis,

    Affiliations: Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada, Department of Medical Genetics and Microbiology, University of Toronto, Toronto, Ontario, Canada

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  • Mark Gagliardi,

    Affiliation: Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada

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  • Judit P Banath,

    Affiliation: British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada

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  • Rachel K Szilard,

    Affiliation: Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada

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  • Shinichiro Nakada,

    Affiliation: Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada

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  • Sarah Galicia,

    Affiliation: Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada

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  • Frederic D Sweeney,

    Affiliations: Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada, Department of Medical Genetics and Microbiology, University of Toronto, Toronto, Ontario, Canada

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  • Diane C Cabelof,

    Affiliation: Karmanos Cancer Institute, Detroit, Michigan, United States of America

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  • Peggy L Olive,

    Affiliation: British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada

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  • Daniel Durocher mail

    To whom correspondence should be addressed. E-mail: durocher@mshri.on.ca

    Affiliations: Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada, Department of Medical Genetics and Microbiology, University of Toronto, Toronto, Ontario, Canada

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  • Published: August 10, 2007
  • DOI: 10.1371/journal.pgen.0030134

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