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Research Article

Adaptive Stress Response in Segmental Progeria Resembles Long-Lived Dwarfism and Calorie Restriction in Mice

  • Marieke van de Ven equal contributor,

    equal contributor Contributed equally to this work with: Marieke van de Ven, Jaan-Olle Andressoo

    Affiliation: Medical Genetics Center, Department of Cell Biology and Genetics, Center of Biomedical Genetics, Erasmus Medical Center, Rotterdam, The Netherlands

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  • Jaan-Olle Andressoo equal contributor,

    equal contributor Contributed equally to this work with: Marieke van de Ven, Jaan-Olle Andressoo

    Affiliation: Medical Genetics Center, Department of Cell Biology and Genetics, Center of Biomedical Genetics, Erasmus Medical Center, Rotterdam, The Netherlands

    ¤ Current address: Institute of Biotechnology, University of Helsinki, Finland

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  • Valerie B Holcomb,

    Affiliation: Department of Molecular Medicine, University of Texas/Institute of Biotechnology, San Antonio, Texas, United States of America

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  • Marieke von Lindern,

    Affiliation: Department of Hematology, Erasmus MC, Rotterdam, The Netherlands

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  • Willeke M. C Jong,

    Affiliation: Medical Genetics Center, Department of Cell Biology and Genetics, Center of Biomedical Genetics, Erasmus Medical Center, Rotterdam, The Netherlands

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  • Chris I. De Zeeuw,

    Affiliation: Department of Neuroscience, Erasmus MC, Rotterdam, The Netherlands

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  • Yousin Suh,

    Affiliation: Department of Molecular Medicine, University of Texas/Institute of Biotechnology, San Antonio, Texas, United States of America

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  • Paul Hasty,

    Affiliation: Department of Molecular Medicine, University of Texas/Institute of Biotechnology, San Antonio, Texas, United States of America

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  • Jan H. J Hoeijmakers,

    Affiliation: Medical Genetics Center, Department of Cell Biology and Genetics, Center of Biomedical Genetics, Erasmus Medical Center, Rotterdam, The Netherlands

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  • Gijsbertus T. J van der Horst,

    Affiliation: Medical Genetics Center, Department of Cell Biology and Genetics, Center of Biomedical Genetics, Erasmus Medical Center, Rotterdam, The Netherlands

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  • James R Mitchell mail

    To whom correspondence should be addressed. E-mail: j.mitchell@erasmusmc.nl

    Affiliation: Medical Genetics Center, Department of Cell Biology and Genetics, Center of Biomedical Genetics, Erasmus Medical Center, Rotterdam, The Netherlands

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  • Published: December 15, 2006
  • DOI: 10.1371/journal.pgen.0020192

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