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Research Article

Loss of Atrx Affects Trophoblast Development and the Pattern of X-Inactivation in Extraembryonic Tissues

  • David Garrick,

    Affiliation: MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom

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  • Jackie A Sharpe,

    Affiliation: MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom

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  • Ruth Arkell,

    Affiliation: MRC Mammalian Genetics Unit, Harwell, Oxfordshire, United Kingdom

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  • Lorraine Dobbie,

    Affiliation: Institute for Stem Cell Research, University of Edinburgh, Edinburgh, United Kingdom

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  • Andrew J. H Smith,

    Affiliation: Institute for Stem Cell Research, University of Edinburgh, Edinburgh, United Kingdom

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  • William G Wood,

    Affiliation: MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom

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  • Douglas R Higgs,

    Affiliation: MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom

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  • Richard J Gibbons mail

    To whom correspondence should be addressed. E-mail: richard.gibbons@molecular-medicine.oxford.ac.uk

    Affiliation: MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom

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  • Published: April 21, 2006
  • DOI: 10.1371/journal.pgen.0020058

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