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Table of Contents: October 2012

COVER

Gene conversion in Arabidopsis tetrads.

Image Credit: Yujin Sun and Gregory P. Copenhaver (The University of North Carolina at Chapel Hill).
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Mendel established that heterozygous alleles typically segregate in a 2:2 ratio during meiosis. The molecular events that accompany meiotic recombination can also cause a nonreciprocal exchange of information between parental chromosomes that results in a non-Mendelian 3:1 segregation pattern called gene conversion. In this issue, Sun et al. use a visual, pollen tetrad–based assay to measure the frequency of gene conversion across the genome of the model plant Arabidopsis thaliana.

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