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Table of Contents: November 2007

COVER

A Mongolian gerbil spermatocyte at anaphase I

Image Credit: Photo by Roberto de la Fuente.
Issue Image

Chromosome segregation is one of the cornerstones of meiosis. Shown here is a Mongolian gerbil spermatocyte at anaphase I. The X (top) and Y (bottom) chromosomes (labeled in red) are segregating to opposite cell poles while they remain connected by a proteinaceous bridge (see de la Fuente et al., e198). Green, SYCP3 protein; red, ?-H2AX; blue, DNA staining with DAPI.

Review

Research Articles

AGEMAP: A Gene Expression Database for Aging in Mice

Jacob M Zahn, Suresh Poosala, Art B Owen, Donald K Ingram, Ana Lustig, Arnell Carter, Ashani T Weeraratna, Dennis D Taub, Myriam Gorospe, Krystyna Mazan-Mamczarz, Edward G Lakatta, Kenneth R Boheler, Xiangru Xu, Mark P Mattson, Geppino Falco, Minoru S. H Ko, David Schlessinger, Jeffrey Firman, Sarah K Kummerfeld, William H Wood III, Alan B Zonderman, Stuart K Kim, Kevin G Becker

Rrp1b, a New Candidate Susceptibility Gene for Breast Cancer Progression and Metastasis

Nigel P. S Crawford, Xiaolan Qian, Argyrios Ziogas, Alex G Papageorge, Brenda J Boersma, Renard C Walker, Luanne Lukes, William L Rowe, Jinghui Zhang, Stefan Ambs, Douglas R Lowy, Hoda Anton-Culver, Kent W Hunter

Excess Single-Stranded DNA Inhibits Meiotic Double-Strand Break Repair

Rebecca Johnson, Valérie Borde, Matthew J Neale, Anna Bishop-Bailey, Matthew North, Sheila Harris, Alain Nicolas, Alastair S. H Goldman

Genetic Variation and Population Structure in Native Americans

Sijia Wang, Cecil M Lewis Jr., Mattias Jakobsson, Sohini Ramachandran, Nicolas Ray, Gabriel Bedoya, Winston Rojas, Maria V Parra, Julio A Molina, Carla Gallo, Guido Mazzotti, Giovanni Poletti, Kim Hill, Ana M Hurtado, Damian Labuda, William Klitz, Ramiro Barrantes, Maria Cátira Bortolini, Francisco M Salzano, Maria Luiza Petzl-Erler, Luiza T Tsuneto, Elena Llop, Francisco Rothhammer, Laurent Excoffier, Marcus W Feldman, Noah A Rosenberg, Andrés Ruiz-Linares

Activation of Inflammation/NF-κB Signaling in Infants Born to Arsenic-Exposed Mothers

Rebecca C Fry, Panida Navasumrit, Chandni Valiathan, J. Peter Svensson, Bradley J Hogan, Manlin Luo, Sanchita Bhattacharya, Krittinee Kandjanapa, Sumitra Soontararuks, Sumontha Nookabkaew, Chulabhorn Mahidol, Mathuros Ruchirawat, Leona D Samson

Extragenic Accumulation of RNA Polymerase II Enhances Transcription by RNA Polymerase III

Imke Listerman, Anita S Bledau, Inna Grishina, Karla M Neugebauer

A High-Density Admixture Scan in 1,670 African Americans with Hypertension

Rahul C Deo, Nick Patterson, Arti Tandon, Gavin J McDonald, Christopher A Haiman, Kristin Ardlie, Brian E Henderson, Sean O Henderson, David Reich

The “Alternative” Choice of Constitutive Exons throughout Evolution

Galit Lev-Maor, Amir Goren, Noa Sela, Eddo Kim, Hadas Keren, Adi Doron-Faigenboim, Shelly Leibman-Barak, Tal Pupko, Gil Ast

Pre-mRNA Secondary Structures Influence Exon Recognition

Michael Hiller, Zhaiyi Zhang, Rolf Backofen, Stefan Stamm

Forty Years of Erratic Insecticide Resistance Evolution in the Mosquito Culex pipiens

Pierrick Labbé, Claire Berticat, Arnaud Berthomieu, Sandra Unal, Clothilde Bernard, Mylène Weill, Thomas Lenormand

The ets-Related Transcription Factor GABP Directs Bidirectional Transcription

Patrick J Collins, Yuya Kobayashi, Loan Nguyen, Nathan D Trinklein, Richard M Myers

POF and HP1 Bind Expressed Exons, Suggesting a Balancing Mechanism for Gene Regulation

Anna-Mia Johansson, Per Stenberg, Fredrik Pettersson, Jan Larsson

Identification of Two Independent Risk Factors for Lupus within the MHC in United Kingdom Families

Michelle M. A Fernando, Christine R Stevens, Pardis C Sabeti, Emily C Walsh, Alasdair J. M McWhinnie, Anila Shah, Todd Green, John D Rioux, Timothy J Vyse

The GLUT9 Gene Is Associated with Serum Uric Acid Levels in Sardinia and Chianti Cohorts

Siguang Li, Serena Sanna, Andrea Maschio, Fabio Busonero, Gianluca Usala, Antonella Mulas, Sandra Lai, Mariano Dei, Marco Orrù, Giuseppe Albai, Stefania Bandinelli, David Schlessinger, Edward Lakatta, Angelo Scuteri, Samer S Najjar, Jack Guralnik, Silvia Naitza, Laura Crisponi, Antonio Cao, Gonçalo Abecasis, Luigi Ferrucci, Manuela Uda, Wei-Min Chen, Ramaiah Nagaraja

Allelic Heterogeneity at the Equine KIT Locus in Dominant White (W) Horses

Bianca Haase, Samantha A Brooks, Angela Schlumbaum, Pedro J Azor, Ernest Bailey, Ferial Alaeddine, Meike Mevissen, Dominik Burger, Pierre-André Poncet, Stefan Rieder, Tosso Leeb

Gene Family Evolution across 12 Drosophila Genomes

Matthew W Hahn, Mira V Han, Sang-Gook Han

Mutations in Drosophila Greatwall/Scant Reveal Its Roles in Mitosis and Meiosis and Interdependence with Polo Kinase

Vincent Archambault, Xinbei Zhao, Helen White-Cooper, Adelaide T. C Carpenter, David M Glover

Meiotic Pairing and Segregation of Achiasmate Sex Chromosomes in Eutherian Mammals: The Role of SYCP3 Protein

Roberto de la Fuente, María Teresa Parra, Alberto Viera, Adela Calvente, Rocío Gómez, José Ángel Suja, Julio S Rufas, Jesús Page