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Table of Contents: February 2013

COVER

Modifying the modifier: polymorphic variants of the mismatch repair protein MSH3 modify disease-causing CAG/CTG repeat expansions.

Image Credit: Christopher E. Pearson and Colin T. Pearson, The Hospital for Sick Children.
Issue Image

The mismatch repair protein MSH3 is required to drive disease-causing CAG/CTG repeat expansions in Huntington's disease and myotonic dystrophy mice, contrary to its canonical role of mutation avoidance, making MSH3 the major modifier of repeat instability. In this issue, Tomé and colleagues identify mouse strain-specific variants of Msh3 that modify MSH3 protein levels, which dramatically modify levels of tissue-specific CAG repeat instability, much like a tuning dial modifies the volume of music from a stereo amplifier (as imaged). Since levels of somatic CAG expansions can modulate disease onset, progression, and severity, specific DNA repair gene variants may have prognostic implications.

Research Articles

Rearrangements of 2.5 Kilobases of Noncoding DNA from the Drosophila even-skipped Locus Define Predictive Rules of Genomic cis-Regulatory Logic

Ah-Ram Kim, Carlos Martinez, John Ionides, Alexandre F. Ramos, Michael Z. Ludwig, Nobuo Ogawa, David H. Sharp, John Reinitz

The Interaction of CtIP and Nbs1 Connects CDK and ATM to Regulate HR–Mediated Double-Strand Break Repair

Hailong Wang, Linda Z. Shi, Catherine C. L. Wong, Xuemei Han, Patty Yi-Hwa Hwang, Lan N. Truong, Qingyuan Zhu, Zhengping Shao, David J. Chen, Michael W. Berns, John R. Yates III, Longchuan Chen, Xiaohua Wu

MSH3 Polymorphisms and Protein Levels Affect CAG Repeat Instability in Huntington's Disease Mice

Stéphanie Tomé, Kevin Manley, Jodie P. Simard, Greg W. Clark, Meghan M. Slean, Meera Swami, Peggy F. Shelbourne, Elisabeth R. M. Tillier, Darren G. Monckton, Anne Messer, Christopher E. Pearson

Cell Reprogramming Requires Silencing of a Core Subset of Polycomb Targets

Giulia Fragola, Pierre-Luc Germain, Pasquale Laise, Alessandro Cuomo, Alessandro Blasimme, Fridolin Gross, Elena Signaroldi, Gabriele Bucci, Cesar Sommer, Giancarlo Pruneri, Giovanni Mazzarol, Tiziana Bonaldi, Gustavo Mostoslavsky, Stefano Casola, Giuseppe Testa

Genome-Wide Analysis Points to Roles for Extracellular Matrix Remodeling, the Visual Cycle, and Neuronal Development in Myopia

Amy K. Kiefer, Joyce Y. Tung, Chuong B. Do, David A. Hinds, Joanna L. Mountain, Uta Francke, Nicholas Eriksson

Deleterious Alleles in the Human Genome Are on Average Younger Than Neutral Alleles of the Same Frequency

Adam Kiezun, Sara L. Pulit, Laurent C. Francioli, Freerk van Dijk, Morris Swertz, Dorret I. Boomsma, Cornelia M. van Duijn, P. Eline Slagboom, G. J. B. van Ommen, Cisca Wijmenga, Paul I. W. de Bakker, Shamil R. Sunyaev , Genome of the Netherlands Consortium

FAM20A Mutations Can Cause Enamel-Renal Syndrome (ERS)

Shih-Kai Wang, Parissa Aref, Yuanyuan Hu, Rachel N. Milkovich, James P. Simmer, Mohammad El-Khateeb, Hinda Daggag, Zaid H. Baqain, Jan C-C. Hu

Dynamic Association of NUP98 with the Human Genome

Yun Liang, Tobias M. Franks, Maria C. Marchetto, Fred H. Gage, Martin W. Hetzer

A Genome-Wide RNAi Screen in Caenorhabditis elegans Identifies the Nicotinic Acetylcholine Receptor Subunit ACR-7 as an Antipsychotic Drug Target

Taixiang Saur, Sarah E. DeMarco, Angelica Ortiz, Gregory R. Sliwoski, Limin Hao, Xin Wang, Bruce M. Cohen, Edgar A. Buttner

Genome-Wide Diversity in the Levant Reveals Recent Structuring by Culture

Marc Haber, Dominique Gauguier, Sonia Youhanna, Nick Patterson, Priya Moorjani, Laura R. Botigué, Daniel E. Platt, Elizabeth Matisoo-Smith, David F. Soria-Hernanz, R. Spencer Wells, Jaume Bertranpetit, Chris Tyler-Smith, David Comas, Pierre A. Zalloua

ISWI and CHD Chromatin Remodelers Bind Promoters but Act in Gene Bodies

Gabriel E. Zentner, Toshio Tsukiyama, Steven Henikoff

Conditional Inactivation of the DNA Damage Response Gene Hus1 in Mouse Testis Reveals Separable Roles for Components of the RAD9-RAD1-HUS1 Complex in Meiotic Chromosome Maintenance

Amy M. Lyndaker, Pei Xin Lim, Joanna M. Mleczko, Catherine E. Diggins, J. Kim Holloway, Rebecca J. Holmes, Rui Kan, Donald H. Schlafer, Raimundo Freire, Paula E. Cohen, Robert S. Weiss

Plant-Symbiotic Fungi as Chemical Engineers: Multi-Genome Analysis of the Clavicipitaceae Reveals Dynamics of Alkaloid Loci

Christopher L. Schardl, Carolyn A. Young, Uljana Hesse, Stefan G. Amyotte, Kalina Andreeva, Patrick J. Calie, Damien J. Fleetwood, David C. Haws, Neil Moore, Birgitt Oeser, Daniel G. Panaccione, Kathryn K. Schweri, Christine R. Voisey, Mark L. Farman, Jerzy W. Jaromczyk, Bruce A. Roe, Donal M. O'Sullivan, Barry Scott, Paul Tudzynski, Zhiqiang An, Elissaveta G. Arnaoudova, Charles T. Bullock, Nikki D. Charlton, Li Chen, Murray Cox, Randy D. Dinkins, Simona Florea, Anthony E. Glenn, Anna Gordon, Ulrich Güldener, Daniel R. Harris, Walter Hollin, Jolanta Jaromczyk, Richard D. Johnson, Anar K. Khan, Eckhard Leistner, Adrian Leuchtmann, Chunjie Li, JinGe Liu, Jinze Liu, Miao Liu, Wade Mace, Caroline Machado, Padmaja Nagabhyru, Juan Pan, Jan Schmid, Koya Sugawara, Ulrike Steiner, Johanna E. Takach, Eiji Tanaka, Jennifer S. Webb, Ella V. Wilson, Jennifer L. Wiseman, Ruriko Yoshida, Zheng Zeng

Roles of the Developmental Regulator unc-62/Homothorax in Limiting Longevity in Caenorhabditis elegans

Eric L. Van Nostrand, Adolfo Sánchez-Blanco, Beijing Wu, Andy Nguyen, Stuart K. Kim

The Amidation Step of Diphthamide Biosynthesis in Yeast Requires DPH6, a Gene Identified through Mining the DPH1-DPH5 Interaction Network

Shanow Uthman, Christian Bär, Viktor Scheidt, Shihui Liu, Sara ten Have, Flaviano Giorgini, Michael J. R. Stark, Raffael Schaffrath

MicroRNA-3148 Modulates Allelic Expression of Toll-Like Receptor 7 Variant Associated with Systemic Lupus Erythematosus

Yun Deng, Jian Zhao, Daisuke Sakurai, Kenneth M. Kaufman, Jeffrey C. Edberg, Robert P. Kimberly, Diane L. Kamen, Gary S. Gilkeson, Chaim O. Jacob, R. Hal Scofield, Carl D. Langefeld, Jennifer A. Kelly, Rosalind Ramsey-Goldman, Michelle A. Petri, John D. Reveille, Luis M. Vilá, Graciela S. Alarcón, Timothy J. Vyse, Bernardo A. Pons-Estel, Barry I. Freedman, Patrick M. Gaffney, Kathy Moser Sivils, Judith A. James, Peter K. Gregersen, Juan-Manuel Anaya, Timothy B. Niewold, Joan T. Merrill, Lindsey A. Criswell, Anne M. Stevens, Susan A. Boackle, Rita M. Cantor, Weiling Chen, Jeniffer M. Grossman, Bevra H. Hahn, John B. Harley, Marta E. Alarcόn-Riquelme, Elizabeth E. Brown, Betty P. Tsao , on behalf of the Argentine Collaborative Group, on behalf of the BIOLUPUS and GENLES networks

Ectopic Expression of Ptf1a Induces Spinal Defects, Urogenital Defects, and Anorectal Malformations in Danforth's Short Tail Mice

Kei Semba, Kimi Araki, Ken-ichirou Matsumoto, Hiroko Suda, Takashi Ando, Akira Sei, Hiroshi Mizuta, Katsumasa Takagi, Mai Nakahara, Mayumi Muta, Gen Yamada, Naomi Nakagata, Aritoshi Iida, Shiro Ikegawa, Yusuke Nakamura, Masatake Araki, Kuniya Abe, Ken-ichi Yamamura

Genetic Determinants of Trabecular and Cortical Volumetric Bone Mineral Densities and Bone Microstructure

Lavinia Paternoster, Mattias Lorentzon, Terho Lehtimäki, Joel Eriksson, Mika Kähönen, Olli Raitakari, Marika Laaksonen, Harri Sievänen, Jorma Viikari, Leo-Pekka Lyytikäinen, Dan Mellström, Magnus Karlsson, Östen Ljunggren, Elin Grundberg, John P. Kemp, Adrian Sayers, Maria Nethander, David M. Evans, Liesbeth Vandenput, Jon H. Tobias, Claes Ohlsson

Ehd4 Encodes a Novel and Oryza-Genus-Specific Regulator of Photoperiodic Flowering in Rice

He Gao, Xiao-Ming Zheng, Guilin Fei, Jun Chen, Mingna Jin, Yulong Ren, Weixun Wu, Kunneng Zhou, Peike Sheng, Feng Zhou, Ling Jiang, Jie Wang, Xin Zhang, Xiuping Guo, Jiu-Lin Wang, Zhijun Cheng, Chuanyin Wu, Haiyang Wang, Jian-Min Wan

PcG-Mediated Higher-Order Chromatin Structures Modulate Replication Programs at the Drosophila BX-C

Federica Lo Sardo, Chiara Lanzuolo, Federico Comoglio, Marco De Bardi, Renato Paro, Valerio Orlando

SOX2 Co-Occupies Distal Enhancer Elements with Distinct POU Factors in ESCs and NPCs to Specify Cell State

Michael A. Lodato, Christopher W. Ng, Joseph A. Wamstad, Albert W. Cheng, Kevin K. Thai, Ernest Fraenkel, Rudolf Jaenisch, Laurie A. Boyer

Patterning of Leaf Vein Networks by Convergent Auxin Transport Pathways

Megan G. Sawchuk, Alexander Edgar, Enrico Scarpella

Discovery of a Splicing Regulator Required for Cell Cycle Progression

Elena S. Suvorova, Matthew Croken, Stella Kratzer, Li-Min Ting, Magnolia Conde de Felipe, Bharath Balu, Meng L. Markillie, Louis M. Weiss, Kami Kim, Michael W. White

Mechanisms Involved in the Functional Divergence of Duplicated GroEL Chaperonins in Myxococcus xanthus DK1622

Yan Wang, Wen-yan Zhang, Zheng Zhang, Jian Li, Zhi-feng Li, Zai-gao Tan, Tian-tian Zhang, Zhi-hong Wu, Hong Liu, Yue-zhong Li

Admixture Mapping in Lupus Identifies Multiple Functional Variants within IFIH1 Associated with Apoptosis, Inflammation, and Autoantibody Production

Julio E. Molineros, Amit K. Maiti, Celi Sun, Loren L. Looger, Shizhong Han, Xana Kim-Howard, Stuart Glenn, Adam Adler, Jennifer A. Kelly, Timothy B. Niewold, Gary S. Gilkeson, Elizabeth E. Brown, Graciela S. Alarcón, Jeffrey C. Edberg, Michelle Petri, Rosalind Ramsey-Goldman, John D. Reveille, Luis M. Vilá, Barry I. Freedman, Betty P. Tsao, Lindsey A. Criswell, Chaim O. Jacob, Jason H. Moore, Timothy J. Vyse, Carl L. Langefeld, Joel M. Guthridge, Patrick M. Gaffney, Kathy L. Moser, R. Hal Scofield, Marta E. Alarcón-Riquelme, Scott M. Williams, Joan T. Merrill, Judith A. James, Kenneth M. Kaufman, Robert P. Kimberly, John B. Harley, Swapan K. Nath , on behalf of the BIOLUPUS Network

Hepatocyte Growth Factor, a Determinant of Airspace Homeostasis in the Murine Lung

Carla Calvi, Megan Podowski, Armando Lopez-Mercado, Shana Metzger, Kaori Misono, Alla Malinina, Dustin Dikeman, Hataya Poonyagariyon, Leslie Ynalvez, Roshanak Derakhshandeh, Anne Le, Mark Merchant, Ralph Schwall, Enid R. Neptune

A Kinome-Wide RNAi Screen in Drosophila Glia Reveals That the RIO Kinases Mediate Cell Proliferation and Survival through TORC2-Akt Signaling in Glioblastoma

Renee D. Read, Tim R. Fenton, German G. Gomez, Jill Wykosky, Scott R. Vandenberg, Ivan Babic, Akio Iwanami, Huijun Yang, Webster K. Cavenee, Paul S. Mischel, Frank B. Furnari, John B. Thomas

Massive Mitochondrial Gene Transfer in a Parasitic Flowering Plant Clade

Zhenxiang Xi, Yuguo Wang, Robert K. Bradley, M. Sugumaran, Christopher J. Marx, Joshua S. Rest, Charles C. Davis

Expression of a Novel P22 ORFan Gene Reveals the Phage Carrier State in Salmonella Typhimurium

William Cenens, Mehari T. Mebrhatu, Angella Makumi, Pieter-Jan Ceyssens, Rob Lavigne, Rob Van Houdt, François Taddei, Abram Aertsen

ImmunoChip Study Implicates Antigen Presentation to T Cells in Narcolepsy

Juliette Faraco, Ling Lin, Birgitte Rahbek Kornum, Eimear E. Kenny, Gosia Trynka, Mali Einen, Tom J. Rico, Peter Lichtner, Yves Dauvilliers, Isabelle Arnulf, Michel Lecendreux, Sirous Javidi, Peter Geisler, Geert Mayer, Fabio Pizza, Francesca Poli, Giuseppe Plazzi, Sebastiaan Overeem, Gert Jan Lammers, David Kemlink, Karel Sonka, Sona Nevsimalova, Guy Rouleau, Alex Desautels, Jacques Montplaisir, Birgit Frauscher, Laura Ehrmann, Birgit Högl, Poul Jennum, Patrice Bourgin, Rosa Peraita-Adrados, Alex Iranzo, Claudio Bassetti, Wei-Min Chen, Patrick Concannon, Susan D. Thompson, Vincent Damotte, Bertrand Fontaine, Maxime Breban, Christian Gieger, Norman Klopp, Panos Deloukas, Cisca Wijmenga, Joachim Hallmayer, Suna Onengut-Gumuscu, Stephen S. Rich, Juliane Winkelmann, Emmanuel Mignot

Tysnd1 Deficiency in Mice Interferes with the Peroxisomal Localization of PTS2 Enzymes, Causing Lipid Metabolic Abnormalities and Male Infertility

Yumi Mizuno, Yuichi Ninomiya, Yutaka Nakachi, Mioko Iseki, Hiroyasu Iwasa, Masumi Akita, Tohru Tsukui, Nobuyuki Shimozawa, Chizuru Ito, Kiyotaka Toshimori, Megumi Nishimukai, Hiroshi Hara, Ryouta Maeba, Tomoki Okazaki, Ali Nasser Ali Alodaib, Mohammed Al Amoudi, Minnie Jacob, Fowzan S. Alkuraya, Yasushi Horai, Mitsuhiro Watanabe, Hiromi Motegi, Shigeharu Wakana, Tetsuo Noda, Igor V. Kurochkin, Yosuke Mizuno, Christian Schönbach, Yasushi Okazaki

miR-199a-5p Is Upregulated during Fibrogenic Response to Tissue Injury and Mediates TGFbeta-Induced Lung Fibroblast Activation by Targeting Caveolin-1

Christian Lacks Lino Cardenas, Imène Sarah Henaoui, Elisabeth Courcot, Christoph Roderburg, Christelle Cauffiez, Sébastien Aubert, Marie-Christine Copin, Benoit Wallaert, François Glowacki, Edmone Dewaeles, Jadranka Milosevic, Julien Maurizio, John Tedrow, Brice Marcet, Jean-Marc Lo-Guidice, Naftali Kaminski, Pascal Barbry, Tom Luedde, Michael Perrais, Bernard Mari, Nicolas Pottier

Ancient DNA Reveals Prehistoric Gene-Flow from Siberia in the Complex Human Population History of North East Europe

Clio Der Sarkissian, Oleg Balanovsky, Guido Brandt, Valery Khartanovich, Alexandra Buzhilova, Sergey Koshel, Valery Zaporozhchenko, Detlef Gronenborn, Vyacheslav Moiseyev, Eugen Kolpakov, Vladimir Shumkin, Kurt W. Alt, Elena Balanovska, Alan Cooper, Wolfgang Haak , the Genographic Consortium

The Prefoldin Bud27 Mediates the Assembly of the Eukaryotic RNA Polymerases in an Rpb5-Dependent Manner

María Carmen Mirón-García, Ana Isabel Garrido-Godino, Varinia García-Molinero, Francisco Hernández-Torres, Susana Rodríguez-Navarro, Francisco Navarro

The Mub1/Ubr2 Ubiquitin Ligase Complex Regulates the Conserved Dsn1 Kinetochore Protein

Bungo Akiyoshi, Christian R. Nelson, Nicole Duggan, Steven Ceto, Jeffrey A. Ranish, Sue Biggins

Genetic Landscape of Open Chromatin in Yeast

Kibaick Lee, Sang Cheol Kim, Inkyung Jung, Kwoneel Kim, Jungmin Seo, Heun-Sik Lee, Gireesh K. Bogu, Dongsup Kim, Sanghyuk Lee, Byungwook Lee, Jung Kyoon Choi

Altered Cohesin Gene Dosage Affects Mammalian Meiotic Chromosome Structure and Behavior

Brenda Murdoch, Nichole Owen, Michelle Stevense, Helen Smith, So Nagaoka, Terry Hassold, Michael McKay, Huiling Xu, Jun Fu, Ekaterina Revenkova, Rolf Jessberger, Patricia Hunt

Complex Inheritance of Melanoma and Pigmentation of Coat and Skin in Grey Horses

Ino Curik, Thomas Druml, Monika Seltenhammer, Elisabeth Sundström, Gerli Rosengren Pielberg, Leif Andersson, Johann Sölkner

Assembly of the Auditory Circuitry by a Hox Genetic Network in the Mouse Brainstem

Maria Di Bonito, Yuichi Narita, Bice Avallone, Luigi Sequino, Marta Mancuso, Gennaro Andolfi, Anna Maria Franzè, Luis Puelles, Filippo M. Rijli, Michèle Studer

DNA–Methylome Analysis of Mouse Intestinal Adenoma Identifies a Tumour-Specific Signature That Is Partly Conserved in Human Colon Cancer

Christina Grimm, Lukas Chavez, Mireia Vilardell, Alexandra L. Farrall, Sascha Tierling, Julia W. Böhm, Phillip Grote, Matthias Lienhard, Jörn Dietrich, Bernd Timmermann, Jörn Walter, Michal R. Schweiger, Hans Lehrach, Ralf Herwig, Bernhard G. Herrmann, Markus Morkel

Antagonism Versus Cooperativity with TALE Cofactors at the Base of the Functional Diversification of Hox Protein Function

María Luisa Rivas, Jose Manuel Espinosa-Vázquez, Nagraj Sambrani, Stephen Greig, Samir Merabet, Yacine Graba, James Castelli-Gair Hombría

Single Transmembrane Peptide DinQ Modulates Membrane-Dependent Activities

Ragnhild Weel-Sneve, Knut Ivan Kristiansen, Ingvild Odsbu, Bjørn Dalhus, James Booth, Torbjørn Rognes, Kirsten Skarstad, Magnar Bjørås

Polygenic Modeling with Bayesian Sparse Linear Mixed Models

Xiang Zhou, Peter Carbonetto, Matthew Stephens

A Meta-Analysis of Thyroid-Related Traits Reveals Novel Loci and Gender-Specific Differences in the Regulation of Thyroid Function

Eleonora Porcu, Marco Medici, Giorgio Pistis, Claudia B. Volpato, Scott G. Wilson, Anne R. Cappola, Steffan D. Bos, Joris Deelen, Martin den Heijer, Rachel M. Freathy, Jari Lahti, Chunyu Liu, Lorna M. Lopez, Ilja M. Nolte, Jeffrey R. O'Connell, Toshiko Tanaka, Stella Trompet, Alice Arnold, Stefania Bandinelli, Marian Beekman, Stefan Böhringer, Suzanne J. Brown, Brendan M. Buckley, Clara Camaschella, Anton J. M. de Craen, Gail Davies, Marieke C. H. de Visser, Ian Ford, Tom Forsen, Timothy M. Frayling, Laura Fugazzola, Martin Gögele, Andrew T. Hattersley, Ad R. Hermus, Albert Hofman, Jeanine J. Houwing-Duistermaat, Richard A. Jensen, Eero Kajantie, Margreet Kloppenburg, Ee M. Lim, Corrado Masciullo, Stefano Mariotti, Cosetta Minelli, Braxton D. Mitchell, Ramaiah Nagaraja, Romana T. Netea-Maier, Aarno Palotie, Luca Persani, Maria G. Piras, Bruce M. Psaty, Katri Räikkönen, J. Brent Richards, Fernando Rivadeneira, Cinzia Sala, Mona M. Sabra, Naveed Sattar, Beverley M. Shields, Nicole Soranzo, John M. Starr, David J. Stott, Fred C. G. J. Sweep, Gianluca Usala, Melanie M. van der Klauw, Diana van Heemst, Alies van Mullem, Sita H.Vermeulen, W. Edward Visser, John P. Walsh, Rudi G. J. Westendorp, Elisabeth Widen, Guangju Zhai, Francesco Cucca, Ian J. Deary, Johan G. Eriksson, Luigi Ferrucci, Caroline S. Fox, J. Wouter Jukema, Lambertus A. Kiemeney, Peter P. Pramstaller, David Schlessinger, Alan R. Shuldiner, Eline P. Slagboom, André G. Uitterlinden, Bijay Vaidya, Theo J. Visser, Bruce H. R. Wolffenbuttel, Ingrid Meulenbelt, Jerome I. Rotter, Tim D. Spector, Andrew A. Hicks, Daniela Toniolo, Serena Sanna, Robin P. Peeters, Silvia Naitza

DNA Methylation Mediated Control of Gene Expression Is Critical for Development of Crown Gall Tumors

Jochen Gohlke, Claus-Juergen Scholz, Susanne Kneitz, Dana Weber, Joerg Fuchs, Rainer Hedrich, Rosalia Deeken

Control of Multicellular Development by the Physically Interacting Deneddylases DEN1/DenA and COP9 Signalosome

Martin Christmann, Tilo Schmaler, Colin Gordon, Xiaohua Huang, Özgür Bayram, Josua Schinke, Sina Stumpf, Wolfgang Dubiel, Gerhard H. Braus

Autophagy Induction Is a Tor- and Tp53-Independent Cell Survival Response in a Zebrafish Model of Disrupted Ribosome Biogenesis

Yeliz Boglev, Andrew P. Badrock, Andrew J. Trotter, Qian Du, Elsbeth J. Richardson, Adam C. Parslow, Sebastian J. Markmiller, Nathan E. Hall, Tanya A. de Jong-Curtain, Annie Y. Ng, Heather Verkade, Elke A. Ober, Holly A. Field, Donghun Shin, Chong H. Shin, Katherine M. Hannan, Ross D. Hannan, Richard B. Pearson, Seok-Hyung Kim, Kevin C. Ess, Graham J. Lieschke, Didier Y. R. Stainier, Joan K. Heath

Drosophila Yemanuclein and HIRA Cooperate for De Novo Assembly of H3.3-Containing Nucleosomes in the Male Pronucleus

Guillermo A. Orsi, Ahmed Algazeery, Régis E. Meyer, Michèle Capri, Laure M. Sapey-Triomphe, Béatrice Horard, Henri Gruffat, Pierre Couble, Ounissa Aït-Ahmed, Benjamin Loppin

Mitotic Evolution of Plasmodium falciparum Shows a Stable Core Genome but Recombination in Antigen Families

Selina E. R. Bopp, Micah J. Manary, A. Taylor Bright, Geoffrey L. Johnston, Neekesh V. Dharia, Fabio L. Luna, Susan McCormack, David Plouffe, Case W. McNamara, John R. Walker, David A. Fidock, Eros Lazzerini Denchi, Elizabeth A. Winzeler

Essential Developmental, Genomic Stability, and Tumour Suppressor Functions of the Mouse Orthologue of hSSB1/NABP2

Wei Shi, Amanda L. Bain, Bjoern Schwer, Fares Al-Ejeh, Corey Smith, Lee Wong, Hua Chai, Mariska S. Miranda, Uda Ho, Makoto Kawaguchi, Yutaka Miura, John W. Finnie, Meaghan Wall, Jörg Heierhorst, Carol Wicking, Kevin J. Spring, Frederick W. Alt, Kum Kum Khanna