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Table of Contents: February 2007

COVER

Male and female Eyprepocnemis plorans

Image Credit: Photograph by Julio S. Rufas.
Issue Image

The same characteristics that made grasshoppers exquisite models for classical cytogenetic studies - few, large chromosomes and well-defined meiotic stages at the cytological level - also make them excellent organisms in which to study protein immunolocalization during meiosis. Shown here are male (top) and female (bottom) Eyprepocnemis plorans (see Valdeolmillos et al., e28).

Editorial

An Age-Old Problem

Nicholas Katsanis, Susan M Rosenberg

Review

The Role of Mitochondrial DNA Mutations in Mammalian Aging

Gregory C Kujoth, Patrick C Bradshaw, Suraiya Haroon, Tomas A Prolla

Research Articles

Sequential Loading of Cohesin Subunits during the First Meiotic Prophase of Grasshoppers

Ana M Valdeolmillos, Alberto Viera, Jesús Page, Ignacio Prieto, Juan L Santos, María Teresa Parra, Margarete M. S Heck, Carlos Martínez-A, José L Barbero, José A Suja, Julio S Rufas

Large-Scale Evaluation of Candidate Genes Identifies Associations between VEGF Polymorphisms and Bladder Cancer Risk

Montserrat García-Closas, Núria Malats, Francisco X Real, Meredith Yeager, Robert Welch, Debra Silverman, Manolis Kogevinas, Mustafa Dosemeci, Jonine Figueroa, Nilanjan Chatterjee, Adonina Tardón, Consol Serra, Alfredo Carrato, Reina García-Closas, Cristiane Murta-Nascimento, Nathaniel Rothman, Stephen J Chanock

Elevated Rates of Sister Chromatid Exchange at Chromosome Ends

M. Katharine Rudd, Cynthia Friedman, Sean S Parghi, Elena V Linardopoulou, Li Hsu, Barbara J Trask

Inducible and Reversible Clock Gene Expression in Brain Using the tTA System for the Study of Circadian Behavior

Hee-Kyung Hong, Jason L Chong, Weimin Song, Eun Joo Song, Amira A Jyawook, Andrew C Schook, Caroline H Ko, Joseph S Takahashi

Meningococcal Genetic Variation Mechanisms Viewed through Comparative Analysis of Serogroup C Strain FAM18

Stephen D Bentley, George S Vernikos, Lori A. S Snyder, Carol Churcher, Claire Arrowsmith, Tracey Chillingworth, Ann Cronin, Paul H Davis, Nancy E Holroyd, Kay Jagels, Mark Maddison, Sharon Moule, Ester Rabbinowitsch, Sarah Sharp, Louise Unwin, Sally Whitehead, Michael A Quail, Mark Achtman, Bart Barrell, Nigel J Saunders, Julian Parkhill

Genetic and Pharmacological Factors That Influence Reproductive Aging in Nematodes

Stacie E Hughes, Kimberley Evason, Chengjie Xiong, Kerry Kornfeld

An Unmethylated 3′ Promoter-Proximal Region Is Required for Efficient Transcription Initiation

Ruth Appanah, David R Dickerson, Preeti Goyal, Mark Groudine, Matthew C Lorincz

A Screen for Retrotransposed Imprinted Genes Reveals an Association between X Chromosome Homology and Maternal Germ-Line Methylation

Andrew J Wood, Roland G Roberts, David Monk, Gudrun E Moore, Reiner Schulz, Rebecca J Oakey

New Small Nuclear RNA Gene-Like Transcriptional Units as Sources of Regulatory Transcripts

Aldo Pagano, Manuele Castelnuovo, Federico Tortelli, Roberto Ferrari, Giorgio Dieci, Ranieri Cancedda

Correction