Advertisement
Research Article

A 660-Kb Deletion with Antagonistic Effects on Fertility and Milk Production Segregates at High Frequency in Nordic Red Cattle: Additional Evidence for the Common Occurrence of Balancing Selection in Livestock

  • Naveen Kumar Kadri,

    Affiliation: Center for Quantitative Genetics and Genomics, Department of Molecular Biology and Genetics, Aarhus University, Tjele, Denmark

    X
  • Goutam Sahana mail,

    goutam.sahana@agrsci.dk (GS); tom.druet@ulg.ac.be (TD)

    Affiliation: Center for Quantitative Genetics and Genomics, Department of Molecular Biology and Genetics, Aarhus University, Tjele, Denmark

    X
  • Carole Charlier,

    Affiliation: Unit of Animal Genomics, GIGA-R & Faculty of Veterinary Medicine, University of Liège (B34), Liège, Belgium

    X
  • Terhi Iso-Touru,

    Affiliation: MTT Agrifood Research Finland, Biotechnology and Food Research, Jokioinen, Finland

    X
  • Bernt Guldbrandtsen,

    Affiliation: Center for Quantitative Genetics and Genomics, Department of Molecular Biology and Genetics, Aarhus University, Tjele, Denmark

    X
  • Latifa Karim,

    Affiliation: Unit of Animal Genomics, GIGA-R & Faculty of Veterinary Medicine, University of Liège (B34), Liège, Belgium

    X
  • Ulrik Sander Nielsen,

    Affiliation: Danish Agricultural Advisory Service, Aarhus N, Denmark

    X
  • Frank Panitz,

    Affiliation: Molecular Genetics and Systems Biology, Department of Molecular Biology and Genetics, Aarhus University, Tjele, Denmark

    X
  • Gert Pedersen Aamand,

    Affiliation: Nordic Cattle Genetic Evaluation, Aarhus N, Denmark

    X
  • Nina Schulman,

    Affiliation: MTT Agrifood Research Finland, Biotechnology and Food Research, Jokioinen, Finland

    X
  • Michel Georges,

    Affiliation: Unit of Animal Genomics, GIGA-R & Faculty of Veterinary Medicine, University of Liège (B34), Liège, Belgium

    X
  • Johanna Vilkki,

    Affiliation: MTT Agrifood Research Finland, Biotechnology and Food Research, Jokioinen, Finland

    X
  • Mogens Sandø Lund,

    Affiliation: Center for Quantitative Genetics and Genomics, Department of Molecular Biology and Genetics, Aarhus University, Tjele, Denmark

    X
  • Tom Druet mail

    goutam.sahana@agrsci.dk (GS); tom.druet@ulg.ac.be (TD)

    Affiliation: Unit of Animal Genomics, GIGA-R & Faculty of Veterinary Medicine, University of Liège (B34), Liège, Belgium

    X
  • Published: January 02, 2014
  • DOI: 10.1371/journal.pgen.1004049

About the Authors

Naveen Kumar Kadri, Goutam Sahana, Bernt Guldbrandtsen, Mogens Sandø Lund
Center for Quantitative Genetics and Genomics, Department of Molecular Biology and Genetics, Aarhus University, Tjele, Denmark
Carole Charlier, Latifa Karim, Michel Georges, Tom Druet
Unit of Animal Genomics, GIGA-R & Faculty of Veterinary Medicine, University of Liège (B34), Liège, Belgium
Terhi Iso-Touru, Nina Schulman, Johanna Vilkki
MTT Agrifood Research Finland, Biotechnology and Food Research, Jokioinen, Finland
Ulrik Sander Nielsen
Danish Agricultural Advisory Service, Aarhus N, Denmark
Frank Panitz
Molecular Genetics and Systems Biology, Department of Molecular Biology and Genetics, Aarhus University, Tjele, Denmark
Gert Pedersen Aamand
Nordic Cattle Genetic Evaluation, Aarhus N, Denmark

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NKK GS BG MSL CC MG TD. Performed the experiments: NKK LK USN. Analyzed the data: NKK BG CC MG TD. Contributed reagents/materials/analysis tools: GS BG MSL JV TIT NS GPA FP TD. Wrote the paper: MG NKK CC TD.