Advertisement
Research Article

The Light Skin Allele of SLC24A5 in South Asians and Europeans Shares Identity by Descent

  • Chandana Basu Mallick equal contributor mail,

    equal contributor Contributed equally to this work with: Chandana Basu Mallick, Florin Mircea Iliescu

    cbm@ebc.ee (CBM); tk331@cam.ac.uk (TK)

    Affiliations: Department of Evolutionary Biology, Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia, Estonian Biocentre, Tartu, Estonia

    X
  • Florin Mircea Iliescu equal contributor,

    equal contributor Contributed equally to this work with: Chandana Basu Mallick, Florin Mircea Iliescu

    Affiliation: Division of Biological Anthropology, University of Cambridge, Cambridge, United Kingdom

    X
  • Märt Möls,

    Affiliations: Estonian Biocentre, Tartu, Estonia, Institute of Mathematical Statistics, University of Tartu, Tartu, Estonia

    X
  • Sarah Hill,

    Affiliation: Division of Biological Anthropology, University of Cambridge, Cambridge, United Kingdom

    X
  • Rakesh Tamang,

    Affiliation: CSIR-Centre for Cellular and Molecular Biology, Hyderabad, India

    X
  • Gyaneshwer Chaubey,

    Affiliation: Estonian Biocentre, Tartu, Estonia

    X
  • Rie Goto,

    Affiliation: Division of Biological Anthropology, University of Cambridge, Cambridge, United Kingdom

    X
  • Simon Y. W. Ho,

    Affiliation: School of Biological Sciences, University of Sydney, Sydney, Australia

    X
  • Irene Gallego Romero,

    Affiliation: Division of Biological Anthropology, University of Cambridge, Cambridge, United Kingdom

    Current address: Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America.

    X
  • Federica Crivellaro,

    Affiliation: Leverhulme Centre for Human Evolutionary Studies, University of Cambridge, Cambridge, United Kingdom

    Current address: National Museum of Prehistory and Ethnography “Luigi Pigorini”, Rome, Italy.

    X
  • Georgi Hudjashov,

    Affiliations: Department of Evolutionary Biology, Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia, Estonian Biocentre, Tartu, Estonia

    X
  • Niraj Rai,

    Affiliation: CSIR-Centre for Cellular and Molecular Biology, Hyderabad, India

    X
  • Mait Metspalu,

    Affiliations: Department of Evolutionary Biology, Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia, Estonian Biocentre, Tartu, Estonia

    X
  • C. G. Nicholas Mascie-Taylor,

    Affiliation: Division of Biological Anthropology, University of Cambridge, Cambridge, United Kingdom

    X
  • Ramasamy Pitchappan,

    Affiliation: Chettinad Academy of Research and Education, Chettinad Health City, Chennai, India

    X
  • Lalji Singh,

    Affiliations: CSIR-Centre for Cellular and Molecular Biology, Hyderabad, India, Banaras Hindu University, Varanasi, India

    X
  • Marta Mirazon-Lahr,

    Affiliation: Leverhulme Centre for Human Evolutionary Studies, University of Cambridge, Cambridge, United Kingdom

    X
  • Kumarasamy Thangaraj,

    Affiliation: CSIR-Centre for Cellular and Molecular Biology, Hyderabad, India

    X
  • Richard Villems,

    Affiliations: Department of Evolutionary Biology, Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia, Estonian Biocentre, Tartu, Estonia, Estonian Academy of Sciences, Tallinn, Estonia

    X
  • Toomas Kivisild mail

    cbm@ebc.ee (CBM); tk331@cam.ac.uk (TK)

    Affiliations: Department of Evolutionary Biology, Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia, Estonian Biocentre, Tartu, Estonia, Division of Biological Anthropology, University of Cambridge, Cambridge, United Kingdom

    X
  • Published: November 07, 2013
  • DOI: 10.1371/journal.pgen.1003912

About the Authors

Chandana Basu Mallick, Georgi Hudjashov, Mait Metspalu, Richard Villems, Toomas Kivisild
Department of Evolutionary Biology, Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia
Chandana Basu Mallick, Märt Möls, Gyaneshwer Chaubey, Georgi Hudjashov, Mait Metspalu, Richard Villems, Toomas Kivisild
Estonian Biocentre, Tartu, Estonia
Florin Mircea Iliescu, Sarah Hill, Rie Goto, Irene Gallego Romero, C. G. Nicholas Mascie-Taylor, Toomas Kivisild
Division of Biological Anthropology, University of Cambridge, Cambridge, United Kingdom
Märt Möls
Institute of Mathematical Statistics, University of Tartu, Tartu, Estonia
Rakesh Tamang, Niraj Rai, Lalji Singh, Kumarasamy Thangaraj
CSIR-Centre for Cellular and Molecular Biology, Hyderabad, India
Simon Y. W. Ho
School of Biological Sciences, University of Sydney, Sydney, Australia
Federica Crivellaro, Marta Mirazon-Lahr
Leverhulme Centre for Human Evolutionary Studies, University of Cambridge, Cambridge, United Kingdom
Ramasamy Pitchappan
Chettinad Academy of Research and Education, Chettinad Health City, Chennai, India
Lalji Singh
Banaras Hindu University, Varanasi, India
Richard Villems
Estonian Academy of Sciences, Tallinn, Estonia

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CBM FMI TK. Performed the experiments: CBM FMI RT. Analyzed the data: CBM FMI MMö RG GC SYWH TK. Contributed reagents/materials/analysis tools: IGR FC NR MMe CGNMT RP MML LS KT RV. Wrote the paper: CBM FMI TK. Supervised the statistical analyses related to genotype-phenotype association study: MMö. Gave suggestions and advice for the logistic regression analysis: RG CGNMT. Helped in performing the selection tests for sequence data using COSI package: GH. Supervised results and discussion related to BEAST analysis: SYWH. Critical editing of the manuscript: SH SYWH RV.