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Research Article

RNAi–Based Functional Profiling of Loci from Blood Lipid Genome-Wide Association Studies Identifies Genes with Cholesterol-Regulatory Function

  • Peter Blattmann,

    Affiliations: Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany, Molecular Medicine Partnership Unit (MMPU), European Molecular Biology Laboratory, Heidelberg, Germany

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  • Christian Schuberth,

    Affiliations: Molecular Medicine Partnership Unit (MMPU), European Molecular Biology Laboratory, Heidelberg, Germany, Institute of Human Genetics, University of Heidelberg, Heidelberg, Germany

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  • Rainer Pepperkok mail,

    pepperko@embl.de (RP); Heiko.Runz@med.uni-heidelberg.de (HR)

    Affiliations: Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany, Molecular Medicine Partnership Unit (MMPU), European Molecular Biology Laboratory, Heidelberg, Germany

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  • Heiko Runz mail

    pepperko@embl.de (RP); Heiko.Runz@med.uni-heidelberg.de (HR)

    Affiliations: Molecular Medicine Partnership Unit (MMPU), European Molecular Biology Laboratory, Heidelberg, Germany, Institute of Human Genetics, University of Heidelberg, Heidelberg, Germany

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  • Published: February 28, 2013
  • DOI: 10.1371/journal.pgen.1003338

About the Authors

Peter Blattmann, Rainer Pepperkok
Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany
Peter Blattmann, Christian Schuberth, Rainer Pepperkok, Heiko Runz
Molecular Medicine Partnership Unit (MMPU), European Molecular Biology Laboratory, Heidelberg, Germany
Christian Schuberth, Heiko Runz
Institute of Human Genetics, University of Heidelberg, Heidelberg, Germany

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: PB RP HR. Performed the experiments: PB CS. Analyzed the data: PB CS. Wrote the paper: PB HR RP.