# wombat urls ß PLOS Genetics: A Genome-Wide RNAi Screen in Caenorhabditis elegans Identifies the Nicotinic Acetylcholine Receptor Subunit ACR-7 as an Antipsychotic Drug Target
Advertisement
Research Article

A Genome-Wide RNAi Screen in Caenorhabditis elegans Identifies the Nicotinic Acetylcholine Receptor Subunit ACR-7 as an Antipsychotic Drug Target

  • Taixiang Saur,

    Affiliations: Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, United States of America, Mailman Research Center, McLean Hospital, Belmont, Massachusetts, United States of America

    X
  • Sarah E. DeMarco,

    Affiliation: Mailman Research Center, McLean Hospital, Belmont, Massachusetts, United States of America

    X
  • Angelica Ortiz,

    Affiliation: Department of Molecular Pathology, University of Texas–MD Anderson Cancer Center, Houston, Texas, United States of America

    X
  • Gregory R. Sliwoski,

    Affiliation: Department of Pharmacology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

    X
  • Limin Hao,

    Affiliations: Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, United States of America, Mailman Research Center, McLean Hospital, Belmont, Massachusetts, United States of America

    X
  • Xin Wang,

    Affiliations: Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, United States of America, Mailman Research Center, McLean Hospital, Belmont, Massachusetts, United States of America

    X
  • Bruce M. Cohen,

    Affiliations: Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, United States of America, Mailman Research Center, McLean Hospital, Belmont, Massachusetts, United States of America

    X
  • Edgar A. Buttner mail

    ebuttner@partners.org

    Affiliations: Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, United States of America, Mailman Research Center, McLean Hospital, Belmont, Massachusetts, United States of America, Department of Neurology, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Published: February 28, 2013
  • DOI: 10.1371/journal.pgen.1003313

About the Authors

Taixiang Saur, Limin Hao, Xin Wang, Bruce M. Cohen, Edgar A. Buttner
Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, United States of America
Taixiang Saur, Sarah E. DeMarco, Limin Hao, Xin Wang, Bruce M. Cohen, Edgar A. Buttner
Mailman Research Center, McLean Hospital, Belmont, Massachusetts, United States of America
Angelica Ortiz
Department of Molecular Pathology, University of Texas–MD Anderson Cancer Center, Houston, Texas, United States of America
Gregory R. Sliwoski
Department of Pharmacology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
Edgar A. Buttner
Department of Neurology, Harvard Medical School, Boston, Massachusetts, United States of America

Corresponding Author

Email: ebuttner@partners.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TS LH XW BMC EAB. Performed the experiments: TS SED AO GRS LH XW EAB. Analyzed the data: TS SED AO GRS LH XW EAB. Wrote the paper: TS AO LH XW BMC EAB.