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Research Article

FAM20A Mutations Can Cause Enamel-Renal Syndrome (ERS)

  • Shih-Kai Wang,

    Affiliations: Department of Biologic and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor, Michigan, United States of America, Oral Health Sciences Program, University of Michigan School of Dentistry, Ann Arbor, Michigan, United States of America

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  • Parissa Aref,

    Affiliation: Tehran University of Medical Sciences, Tehran, Iran

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  • Yuanyuan Hu,

    Affiliation: Department of Biologic and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor, Michigan, United States of America

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  • Rachel N. Milkovich,

    Affiliation: Department of Biologic and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor, Michigan, United States of America

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  • James P. Simmer,

    Affiliation: Department of Biologic and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor, Michigan, United States of America

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  • Mohammad El-Khateeb,

    Affiliation: Molecular Genetics Laboratory, National Center for Diabetes, Endocrinology, and Genetics (NCDEG), Amman, Jordan

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  • Hinda Daggag,

    Affiliation: Molecular Genetics Laboratory, National Center for Diabetes, Endocrinology, and Genetics (NCDEG), Amman, Jordan

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  • Zaid H. Baqain,

    Affiliation: Faculty of Dentistry, The University of Jordan, Amman, Jordan

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  • Jan C-C. Hu mail

    janhu@umich.edu

    Affiliation: Department of Biologic and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor, Michigan, United States of America

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  • Published: February 28, 2013
  • DOI: 10.1371/journal.pgen.1003302

About the Authors

Shih-Kai Wang, Yuanyuan Hu, Rachel N. Milkovich, James P. Simmer, Jan C-C. Hu
Department of Biologic and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor, Michigan, United States of America
Shih-Kai Wang
Oral Health Sciences Program, University of Michigan School of Dentistry, Ann Arbor, Michigan, United States of America
Parissa Aref
Tehran University of Medical Sciences, Tehran, Iran
Mohammad El-Khateeb, Hinda Daggag
Molecular Genetics Laboratory, National Center for Diabetes, Endocrinology, and Genetics (NCDEG), Amman, Jordan
Zaid H. Baqain
Faculty of Dentistry, The University of Jordan, Amman, Jordan

Corresponding Author

Email: janhu@umich.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: S-KW JPS JC-CH. Performed the experiments: S-KW PA YH RNM ME-K HD ZHB. Analyzed the data: S-KW JPS JC-CH. Contributed reagents/materials/analysis tools: S-KW PA YH RNM JPS ME-K HD ZHB JC-CH. Wrote the paper: S-KW JPS JC-CH.