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Research Article

Zcchc11 Uridylates Mature miRNAs to Enhance Neonatal IGF-1 Expression, Growth, and Survival

  • Matthew R. Jones equal contributor,

    equal contributor Contributed equally to this work with: Matthew R. Jones, Matthew T. Blahna

    Affiliation: Pulmonary Center, Boston University School of Medicine, Boston, Massachusetts, United States of America

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  • Matthew T. Blahna equal contributor,

    equal contributor Contributed equally to this work with: Matthew R. Jones, Matthew T. Blahna

    Affiliations: Pulmonary Center, Boston University School of Medicine, Boston, Massachusetts, United States of America, Molecular and Integrative Physiological Sciences Program, Harvard School of Public Health, Boston, Massachusetts, United States of America

    X
  • Elyse Kozlowski,

    Affiliations: Pulmonary Center, Boston University School of Medicine, Boston, Massachusetts, United States of America, Genetics and Genomics Graduate Program, Boston University School of Medicine, Boston, Massachusetts, United States of America

    X
  • Kori Y. Matsuura,

    Affiliation: Pulmonary Center, Boston University School of Medicine, Boston, Massachusetts, United States of America

    X
  • Joseph D. Ferrari,

    Affiliation: Pulmonary Center, Boston University School of Medicine, Boston, Massachusetts, United States of America

    X
  • Samantha A. Morris,

    Affiliation: Stem Cell Program, Children's Hospital Boston, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Harvard Stem Cell Institute, Boston, Massachusetts, United States of America

    X
  • John T. Powers,

    Affiliation: Stem Cell Program, Children's Hospital Boston, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Harvard Stem Cell Institute, Boston, Massachusetts, United States of America

    X
  • George Q. Daley,

    Affiliation: Stem Cell Program, Children's Hospital Boston, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Harvard Stem Cell Institute, Boston, Massachusetts, United States of America

    X
  • Lee J. Quinton,

    Affiliation: Pulmonary Center, Boston University School of Medicine, Boston, Massachusetts, United States of America

    X
  • Joseph P. Mizgerd mail

    jmizgerd@bu.edu

    Affiliations: Pulmonary Center, Boston University School of Medicine, Boston, Massachusetts, United States of America, Departments of Medicine, Microbiology, and Biochemistry, Boston University School of Medicine, Boston, Massachusetts, United States of America

    X
  • Published: November 29, 2012
  • DOI: 10.1371/journal.pgen.1003105

About the Authors

Matthew R. Jones, Matthew T. Blahna, Elyse Kozlowski, Kori Y. Matsuura, Joseph D. Ferrari, Lee J. Quinton, Joseph P. Mizgerd
Pulmonary Center, Boston University School of Medicine, Boston, Massachusetts, United States of America
Matthew T. Blahna
Molecular and Integrative Physiological Sciences Program, Harvard School of Public Health, Boston, Massachusetts, United States of America
Elyse Kozlowski
Genetics and Genomics Graduate Program, Boston University School of Medicine, Boston, Massachusetts, United States of America
Samantha A. Morris, John T. Powers, George Q. Daley
Stem Cell Program, Children's Hospital Boston, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Harvard Stem Cell Institute, Boston, Massachusetts, United States of America
Joseph P. Mizgerd
Departments of Medicine, Microbiology, and Biochemistry, Boston University School of Medicine, Boston, Massachusetts, United States of America

Corresponding Author

Email: jmizgerd@bu.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MRJ MTB LJQ JPM. Performed the experiments: MRJ MTB KYM JDF EK LJQ SAM JTP GQD. Analyzed the data: MRJ MTB KYM JDF EK LJQ JPM. Wrote the paper: MRJ MTB JPM.