Advertisement
Research Article

A Unified Method for Detecting Secondary Trait Associations with Rare Variants: Application to Sequence Data

  • Dajiang J. Liu mail,

    dajiang@umich.edu (DJL); sleal@bcm.edu (SML)

    Affiliation: Department of Biostatistics, Center of Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America

    X
  • Suzanne M. Leal mail

    dajiang@umich.edu (DJL); sleal@bcm.edu (SML)

    Affiliation: Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Published: November 15, 2012
  • DOI: 10.1371/journal.pgen.1003075

About the Authors

Dajiang J. Liu
Department of Biostatistics, Center of Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America
Suzanne M. Leal
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DJL SML. Performed the experiments: DJL. Analyzed the data: DJL. Contributed reagents/materials/analysis tools: DJL SML. Wrote the paper: DJL SML. Designed the software used in analysis: DJL.