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Research Article

Transcription Elongation and Tissue-Specific Somatic CAG Instability

  • Agathi-Vasiliki Goula,

    Affiliation: Programme of Translational Medicine and Neurogenetics, Institute of Genetics and Molecular and Cellular Biology (IGBMC), UMR 7104-CNRS/INSERM/UdS, Illkirch, France

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  • Agnieszka Stys,

    Affiliation: Programme of Translational Medicine and Neurogenetics, Institute of Genetics and Molecular and Cellular Biology (IGBMC), UMR 7104-CNRS/INSERM/UdS, Illkirch, France

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  • Jackson P. K. Chan,

    Affiliation: Department of Medicine, Imperial College London, Hammersmith Hospital Campus, London, United Kingdom

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  • Yvon Trottier,

    Affiliation: Programme of Translational Medicine and Neurogenetics, Institute of Genetics and Molecular and Cellular Biology (IGBMC), UMR 7104-CNRS/INSERM/UdS, Illkirch, France

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  • Richard Festenstein,

    Affiliation: Department of Medicine, Imperial College London, Hammersmith Hospital Campus, London, United Kingdom

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  • Karine Merienne mail

    merienne@igbmc.fr

    Affiliation: Programme of Translational Medicine and Neurogenetics, Institute of Genetics and Molecular and Cellular Biology (IGBMC), UMR 7104-CNRS/INSERM/UdS, Illkirch, France

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  • Published: November 29, 2012
  • DOI: 10.1371/journal.pgen.1003051

About the Authors

Agathi-Vasiliki Goula, Agnieszka Stys, Yvon Trottier, Karine Merienne
Programme of Translational Medicine and Neurogenetics, Institute of Genetics and Molecular and Cellular Biology (IGBMC), UMR 7104-CNRS/INSERM/UdS, Illkirch, France
Jackson P. K. Chan, Richard Festenstein
Department of Medicine, Imperial College London, Hammersmith Hospital Campus, London, United Kingdom

Corresponding Author

Email: merienne@igbmc.fr

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RF KM. Performed the experiments: A-VG AS JPKC KM. Analyzed the data: A-VG AS JPKC RF KM. Contributed reagents/materials/analysis tools: YT KM. Wrote the paper: RF KM.