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Research Article

A Combination of H2A.Z and H4 Acetylation Recruits Brd2 to Chromatin during Transcriptional Activation

  • Ryan Draker,

    Affiliations: Ontario Cancer Institute, Toronto, Canada, Department of Medical Biophysics, University of Toronto, Toronto, Canada

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  • Marlee K. Ng,

    Affiliation: Department of Biology, York University, Toronto, Canada

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  • Elizabeth Sarcinella,

    Affiliation: Ontario Cancer Institute, Toronto, Canada

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  • Vladimir Ignatchenko,

    Affiliation: Ontario Cancer Institute, Toronto, Canada

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  • Thomas Kislinger,

    Affiliations: Ontario Cancer Institute, Toronto, Canada, Department of Medical Biophysics, University of Toronto, Toronto, Canada

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  • Peter Cheung mail

    pmcheung@yorku.ca

    Affiliations: Ontario Cancer Institute, Toronto, Canada, Department of Medical Biophysics, University of Toronto, Toronto, Canada, Department of Biology, York University, Toronto, Canada

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  • Published: November 08, 2012
  • DOI: 10.1371/journal.pgen.1003047

About the Authors

Ryan Draker, Elizabeth Sarcinella, Vladimir Ignatchenko, Thomas Kislinger, Peter Cheung
Ontario Cancer Institute, Toronto, Canada
Ryan Draker, Thomas Kislinger, Peter Cheung
Department of Medical Biophysics, University of Toronto, Toronto, Canada
Marlee K. Ng, Peter Cheung
Department of Biology, York University, Toronto, Canada

Corresponding Author

Email: pmcheung@yorku.ca

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RD MKN ES PC. Performed the experiments: RD MKN ES TK. Analyzed the data: RD MKN ES VI TK PC. Contributed reagents/materials/analysis tools: VI TK. Wrote the paper: RD PC.