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Research Article

A Targeted Glycan-Related Gene Screen Reveals Heparan Sulfate Proteoglycan Sulfation Regulates WNT and BMP Trans-Synaptic Signaling

  • Neil Dani,

    Affiliation: Department of Biological Sciences and Department of Cell and Developmental Biology, Kennedy Center for Research on Human Development, Vanderbilt University, Nashville, Tennessee, United States of America

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  • Minyeop Nahm,

    Affiliation: Department of Cell and Developmental Biology, Seoul National University, Seoul, Republic of Korea

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  • Seungbok Lee,

    Affiliation: Department of Cell and Developmental Biology, Seoul National University, Seoul, Republic of Korea

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  • Kendal Broadie mail

    kendal.broadie@vanderbilt.edu

    Affiliation: Department of Biological Sciences and Department of Cell and Developmental Biology, Kennedy Center for Research on Human Development, Vanderbilt University, Nashville, Tennessee, United States of America

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  • Published: November 08, 2012
  • DOI: 10.1371/journal.pgen.1003031

About the Authors

Neil Dani, Kendal Broadie
Department of Biological Sciences and Department of Cell and Developmental Biology, Kennedy Center for Research on Human Development, Vanderbilt University, Nashville, Tennessee, United States of America
Minyeop Nahm, Seungbok Lee
Department of Cell and Developmental Biology, Seoul National University, Seoul, Republic of Korea

Corresponding Author

Email: kendal.broadie@vanderbilt.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ND KB. Performed the experiments: ND. Analyzed the data: ND. Contributed reagents/materials/analysis tools: MN SL. Wrote the paper: ND KB.