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Research Article

Mechanisms Employed by Escherichia coli to Prevent Ribonucleotide Incorporation into Genomic DNA by Pol V

  • John P. McDonald,

    Affiliation: Laboratory of Genomic Integrity, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Alexandra Vaisman,

    Affiliation: Laboratory of Genomic Integrity, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Wojciech Kuban,

    Affiliation: Laboratory of Genomic Integrity, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Myron F. Goodman,

    Affiliation: Departments of Biological Sciences and Chemistry, University of Southern California, Los Angeles, California, United States of America

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  • Roger Woodgate mail

    woodgate@nih.gov

    Affiliation: Laboratory of Genomic Integrity, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Published: November 08, 2012
  • DOI: 10.1371/journal.pgen.1003030

About the Authors

John P. McDonald, Alexandra Vaisman, Wojciech Kuban, Roger Woodgate
Laboratory of Genomic Integrity, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United States of America
Myron F. Goodman
Departments of Biological Sciences and Chemistry, University of Southern California, Los Angeles, California, United States of America

Corresponding Author

Email: woodgate@nih.gov

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JPM AV WK RW. Performed the experiments: JPM AV WK RW. Analyzed the data: JPM AV WK MFG RW. Contributed reagents/materials/analysis tools: JPM AV WK MFG RW. Wrote the paper: JPM AV WK MFG RW.