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Research Article

Factors That Promote H3 Chromatin Integrity during Transcription Prevent Promiscuous Deposition of CENP-ACnp1 in Fission Yeast

  • Eun Shik Choi,

    Affiliation: Wellcome Trust Centre for Cell Biology, School of Biological Sciences, The University of Edinburgh, Edinburgh, Scotland, United Kingdom

    Current address: Department of Biological Sciences and Institute of Molecular Biology and Genetics, Seoul National University, Seoul, Korea

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  • Annelie Strålfors,

    Affiliation: Department of Biosciences and Nutrition, Karolinska Institutet, NOVUM, Huddinge, Sweden

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  • Sandra Catania,

    Affiliation: Wellcome Trust Centre for Cell Biology, School of Biological Sciences, The University of Edinburgh, Edinburgh, Scotland, United Kingdom

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  • Araceli G. Castillo,

    Affiliation: Wellcome Trust Centre for Cell Biology, School of Biological Sciences, The University of Edinburgh, Edinburgh, Scotland, United Kingdom

    Current address: Departamento de Genética, Facultad de Biología, Universidad de Malaga, Malaga, Spain

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  • J. Peter Svensson,

    Affiliation: Department of Biosciences and Nutrition, Karolinska Institutet, NOVUM, Huddinge, Sweden

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  • Alison L. Pidoux,

    Affiliation: Wellcome Trust Centre for Cell Biology, School of Biological Sciences, The University of Edinburgh, Edinburgh, Scotland, United Kingdom

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  • Karl Ekwall,

    Affiliation: Department of Biosciences and Nutrition, Karolinska Institutet, NOVUM, Huddinge, Sweden

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  • Robin C. Allshire mail

    robin.allshire@ed.ac.uk

    Affiliation: Wellcome Trust Centre for Cell Biology, School of Biological Sciences, The University of Edinburgh, Edinburgh, Scotland, United Kingdom

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  • Published: September 20, 2012
  • DOI: 10.1371/journal.pgen.1002985

About the Authors

Eun Shik Choi, Sandra Catania, Araceli G. Castillo, Alison L. Pidoux, Robin C. Allshire
Wellcome Trust Centre for Cell Biology, School of Biological Sciences, The University of Edinburgh, Edinburgh, Scotland, United Kingdom
Annelie Strålfors, J. Peter Svensson, Karl Ekwall
Department of Biosciences and Nutrition, Karolinska Institutet, NOVUM, Huddinge, Sweden

Corresponding Author

Email: robin.allshire@ed.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ESC AGC ALP KE RCA. Performed the experiments: ESC AS SC AGC JPS. Analyzed the data: ESC AS SC AGC JPS ALP KE RCA. Wrote the paper: ESC RCA.