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Research Article

Proteome-Wide Analysis of Disease-Associated SNPs That Show Allele-Specific Transcription Factor Binding

  • Falk Butter,

    Affiliation: Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany

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  • Lucy Davison,

    Affiliation: Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom

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  • Tar Viturawong,

    Affiliation: Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany

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  • Marion Scheibe,

    Affiliation: Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany

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  • Michiel Vermeulen,

    Affiliation: Molecular Cancer Research, University Medical Center Utrecht, Utrecht, The Netherlands

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  • John A. Todd,

    Affiliation: Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom

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  • Matthias Mann mail

    mmann@biochem.mpg.de

    Affiliation: Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany

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  • Published: September 27, 2012
  • DOI: 10.1371/journal.pgen.1002982

About the Authors

Falk Butter, Tar Viturawong, Marion Scheibe, Matthias Mann
Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany
Lucy Davison, John A. Todd
Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom
Michiel Vermeulen
Molecular Cancer Research, University Medical Center Utrecht, Utrecht, The Netherlands

Corresponding Author

Email: mmann@biochem.mpg.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: FB MV MM. Performed the experiments: FB LD MS. Analyzed the data: FB. Contributed reagents/materials/analysis tools: TV. Wrote the paper: FB LD TV MS MV JAT MM.