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Research Article

De Novo CNV Formation in Mouse Embryonic Stem Cells Occurs in the Absence of Xrcc4-Dependent Nonhomologous End Joining

  • Martin F. Arlt,

    Affiliation: Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, United States of America

    X
  • Sountharia Rajendran,

    Affiliation: Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, United States of America

    X
  • Shanda R. Birkeland,

    Affiliation: Department of Pathology, University of Michigan, Ann Arbor, Michigan, United States of America

    X
  • Thomas E. Wilson mail,

    wilsonte@umich.edu (TEW); glover@umich.edu (TWG)

    Affiliations: Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, United States of America, Department of Pathology, University of Michigan, Ann Arbor, Michigan, United States of America

    X
  • Thomas W. Glover mail

    wilsonte@umich.edu (TEW); glover@umich.edu (TWG)

    Affiliation: Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, United States of America

    X
  • Published: September 20, 2012
  • DOI: 10.1371/journal.pgen.1002981

About the Authors

Martin F. Arlt, Sountharia Rajendran, Thomas E. Wilson, Thomas W. Glover
Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, United States of America
Shanda R. Birkeland, Thomas E. Wilson
Department of Pathology, University of Michigan, Ann Arbor, Michigan, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MFA TEW TWG. Performed the experiments: MFA SR SRB TEW. Analyzed the data: MFA SR SRB TEW TWG. Wrote the paper: MFA TEW TWG.