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Research Article

A Mutation in the Srrm4 Gene Causes Alternative Splicing Defects and Deafness in the Bronx Waltzer Mouse

  • Yoko Nakano,

    Affiliations: Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America, Inflammation Program, Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America

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  • Israt Jahan,

    Affiliation: Department of Biology, College of Liberal Arts and Sciences, University of Iowa, Iowa City, Iowa, United States of America

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  • Gregory Bonde,

    Affiliation: Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America

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  • Xingshen Sun,

    Affiliation: Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America

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  • Michael S. Hildebrand,

    Affiliation: Department of Otolaryngology–Head and Neck Surgery, Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America

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  • John F. Engelhardt,

    Affiliation: Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America

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  • Richard J. H. Smith,

    Affiliation: Department of Otolaryngology–Head and Neck Surgery, Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America

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  • Robert A. Cornell,

    Affiliation: Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America

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  • Bernd Fritzsch,

    Affiliation: Department of Biology, College of Liberal Arts and Sciences, University of Iowa, Iowa City, Iowa, United States of America

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  • Botond Bánfi mail

    botond-banfi@uiowa.edu

    Affiliations: Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America, Inflammation Program, Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America, Department of Otolaryngology–Head and Neck Surgery, Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America, Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America

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  • Published: October 04, 2012
  • DOI: 10.1371/journal.pgen.1002966

About the Authors

Yoko Nakano, Gregory Bonde, Xingshen Sun, John F. Engelhardt, Robert A. Cornell, Botond Bánfi
Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America
Yoko Nakano, Botond Bánfi
Inflammation Program, Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America
Israt Jahan, Bernd Fritzsch
Department of Biology, College of Liberal Arts and Sciences, University of Iowa, Iowa City, Iowa, United States of America
Michael S. Hildebrand, Richard J. H. Smith, Botond Bánfi
Department of Otolaryngology–Head and Neck Surgery, Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America
Botond Bánfi
Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America

Corresponding Author

Email: botond-banfi@uiowa.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YN RAC BF BB. Performed the experiments: YN IJ GB XS MSH. Analyzed the data: YN IJ GB MSH BF JFE RJHS RAC BB. Wrote the paper: YN BB.