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Research Article

Characterization of Inducible Models of Tay-Sachs and Related Disease

  • Timothy J. Sargeant mail,

    tjs62@cam.ac.uk

    Affiliation: Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom

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  • Deborah J. Drage,

    Affiliation: Central Biomedical Services, School of Clinical Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom

    X
  • Susan Wang,

    Affiliation: Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom

    X
  • Apostolos A. Apostolakis,

    Affiliation: Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom

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  • Timothy M. Cox equal contributor,

    equal contributor Contributed equally to this work with: Timothy M. Cox, M. Begoña Cachón-González

    Affiliation: Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom

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  • M. Begoña Cachón-González equal contributor

    equal contributor Contributed equally to this work with: Timothy M. Cox, M. Begoña Cachón-González

    Affiliation: Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom

    X
  • Published: September 20, 2012
  • DOI: 10.1371/journal.pgen.1002943

About the Authors

Timothy J. Sargeant, Susan Wang, Apostolos A. Apostolakis, Timothy M. Cox, M. Begoña Cachón-González
Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom
Deborah J. Drage
Central Biomedical Services, School of Clinical Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom

Corresponding Author

Email: tjs62@cam.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TJS TMC MBC-G. Performed the experiments: TJS DJD SW AAA. Analyzed the data: TJS TMC MBC-G. Wrote the paper: TJS TMC MBC-G.