Advertisement
Research Article

Ccdc94 Protects Cells from Ionizing Radiation by Inhibiting the Expression of p53

  • Shelly Sorrells,

    Affiliation: Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, United States of America

    X
  • Seth Carbonneau,

    Affiliation: Department of Pediatric Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Erik Harrington,

    Affiliation: Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, United States of America

    X
  • Aye T. Chen,

    Affiliation: Department of Hematology/Oncology, Children's Hospital, Boston, Massachusetts, United States of America

    X
  • Bridgid Hast,

    Affiliation: Department of Cell and Developmental Biology, Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina, United States of America

    X
  • Brett Milash,

    Affiliation: Bioinformatics Shared Resource, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, United States of America

    X
  • Ujwal Pyati,

    Affiliation: Department of Pediatric Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Michael B. Major,

    Affiliation: Department of Cell and Developmental Biology, Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina, United States of America

    X
  • Yi Zhou,

    Affiliation: Department of Hematology/Oncology, Children's Hospital, Boston, Massachusetts, United States of America

    X
  • Leonard I. Zon,

    Affiliation: Department of Hematology/Oncology, Children's Hospital, Boston, Massachusetts, United States of America

    X
  • Rodney A. Stewart,

    Affiliation: Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, United States of America

    X
  • A. Thomas Look mail,

    Thomas_Look@dfci.harvard.edu (ATL); Cicely.Jette@hci.utah.edu (CJ)

    Affiliation: Department of Pediatric Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Cicely Jette mail

    Thomas_Look@dfci.harvard.edu (ATL); Cicely.Jette@hci.utah.edu (CJ)

    Affiliation: Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, United States of America

    X
  • Published: August 30, 2012
  • DOI: 10.1371/journal.pgen.1002922

About the Authors

Shelly Sorrells, Erik Harrington, Rodney A. Stewart, Cicely Jette
Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, United States of America
Seth Carbonneau, Ujwal Pyati, A. Thomas Look
Department of Pediatric Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, United States of America
Aye T. Chen, Yi Zhou, Leonard I. Zon
Department of Hematology/Oncology, Children's Hospital, Boston, Massachusetts, United States of America
Bridgid Hast, Michael B. Major
Department of Cell and Developmental Biology, Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina, United States of America
Brett Milash
Bioinformatics Shared Resource, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CJ SS UP MBM RAS LIZ ATL. Performed the experiments: CJ SS SC EH ATC BH BM. Analyzed the data: CJ SS BM UP BH MBM YZ RAS ATL LIZ. Contributed reagents/materials/analysis tools: CJ MBM BM YZ LIZ ATL. Wrote the paper: CJ SS RAS ATL.