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Research Article

NOL11, Implicated in the Pathogenesis of North American Indian Childhood Cirrhosis, Is Required for Pre-rRNA Transcription and Processing

  • Emily F. Freed,

    Affiliation: Department of Genetics, Yale University School of Medicine, New Haven, Connecticut, United States of America

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  • José-Luis Prieto,

    Affiliation: Centre for Chromosome Biology, School of Life Sciences, National University of Ireland Galway, Galway, Ireland

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  • Kathleen L. McCann,

    Affiliation: Department of Genetics, Yale University School of Medicine, New Haven, Connecticut, United States of America

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  • Brian McStay,

    Affiliation: Centre for Chromosome Biology, School of Life Sciences, National University of Ireland Galway, Galway, Ireland

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  • Susan J. Baserga mail

    susan.baserga@yale.edu

    Affiliations: Department of Genetics, Yale University School of Medicine, New Haven, Connecticut, United States of America, Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, Connecticut, United States of America, Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut, United States of America

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  • Published: August 16, 2012
  • DOI: 10.1371/journal.pgen.1002892

About the Authors

Emily F. Freed, Kathleen L. McCann, Susan J. Baserga
Department of Genetics, Yale University School of Medicine, New Haven, Connecticut, United States of America
José-Luis Prieto, Brian McStay
Centre for Chromosome Biology, School of Life Sciences, National University of Ireland Galway, Galway, Ireland
Susan J. Baserga
Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, Connecticut, United States of America
Susan J. Baserga
Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut, United States of America

Corresponding Author

Email: susan.baserga@yale.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SJB BM EFF. Performed the experiments: EFF J-LP KLM. Analyzed the data: SJB BM EFF J-LP. Contributed reagents/materials/analysis tools: SJB BM EFF J-LP. Wrote the paper: SJB EFF BM J-LP.