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Research Article

SCS3 and YFT2 Link Transcription of Phospholipid Biosynthetic Genes to ER Stress and the UPR

  • Robyn D. Moir,

    Affiliation: Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America

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  • David A. Gross,

    Affiliations: Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America, Signature Research Program in Cardiovascular and Metabolic Disorders, Duke–NUS Graduate Medical School Singapore, Singapore, Singapore

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  • David L. Silver mail,

    ian.willis@einstein.yu.edu (IMW); david.silver@duke-nus.edu.sg (DLS)

    Affiliations: Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America, Signature Research Program in Cardiovascular and Metabolic Disorders, Duke–NUS Graduate Medical School Singapore, Singapore, Singapore

    X
  • Ian M. Willis mail

    ian.willis@einstein.yu.edu (IMW); david.silver@duke-nus.edu.sg (DLS)

    Affiliations: Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America, Department of Systems and Computational Biology, Albert Einstein College of Medicine, Bronx, New York, United States of America

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  • Published: August 23, 2012
  • DOI: 10.1371/journal.pgen.1002890

About the Authors

Robyn D. Moir, David A. Gross, David L. Silver, Ian M. Willis
Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America
David A. Gross, David L. Silver
Signature Research Program in Cardiovascular and Metabolic Disorders, Duke–NUS Graduate Medical School Singapore, Singapore, Singapore
Ian M. Willis
Department of Systems and Computational Biology, Albert Einstein College of Medicine, Bronx, New York, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RDM DLS IMW. Performed the experiments: RDM DAG IMW. Analyzed the data: RDM DLS IMW. Wrote the paper: RDM IMW.