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Research Article

The Secreted Immunoglobulin Domain Proteins ZIG-5 and ZIG-8 Cooperate with L1CAM/SAX-7 to Maintain Nervous System Integrity

  • Claire Y. Bénard mail,

    Claire.Benard@umassmed.edu

    Affiliations: Department of Neurobiology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America, Department of Biochemistry and Molecular Biophysics, Howard Hughes Medical Institute, Columbia University Medical Center, New York, New York, United States of America

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  • Cassandra Blanchette,

    Affiliation: Department of Neurobiology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Janine Recio,

    Affiliations: Department of Neurobiology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America, Department of Biochemistry and Molecular Biophysics, Howard Hughes Medical Institute, Columbia University Medical Center, New York, New York, United States of America

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  • Oliver Hobert

    Affiliation: Department of Biochemistry and Molecular Biophysics, Howard Hughes Medical Institute, Columbia University Medical Center, New York, New York, United States of America

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  • Published: July 19, 2012
  • DOI: 10.1371/journal.pgen.1002819

About the Authors

Claire Y. Bénard, Cassandra Blanchette, Janine Recio
Department of Neurobiology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
Claire Y. Bénard, Janine Recio, Oliver Hobert
Department of Biochemistry and Molecular Biophysics, Howard Hughes Medical Institute, Columbia University Medical Center, New York, New York, United States of America

Corresponding Author

Email: Claire.Benard@umassmed.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CYB OH. Performed the experiments: CYB CB JR. Analyzed the data: CYB OH. Wrote the paper: CYB OH.