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Research Article

The Rad4TopBP1 ATR-Activation Domain Functions in G1/S Phase in a Chromatin-Dependent Manner

  • Su-Jiun Lin equal contributor,

    equal contributor Contributed equally to this work with: Su-Jiun Lin, Christopher P. Wardlaw

    Affiliation: Genome Damage and Stability Centre, University of Sussex, Brighton, Sussex, United Kingdom

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  • Christopher P. Wardlaw equal contributor,

    equal contributor Contributed equally to this work with: Su-Jiun Lin, Christopher P. Wardlaw

    Affiliation: Genome Damage and Stability Centre, University of Sussex, Brighton, Sussex, United Kingdom

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  • Takashi Morishita,

    Affiliation: Genome Damage and Stability Centre, University of Sussex, Brighton, Sussex, United Kingdom

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  • Izumi Miyabe,

    Affiliation: Genome Damage and Stability Centre, University of Sussex, Brighton, Sussex, United Kingdom

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  • Charly Chahwan,

    Affiliation: Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

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  • Thomas Caspari,

    Affiliation: School of Biological Sciences, Bangor University, Bangor, Gwynedd, United Kingdom

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  • Ulrike Schmidt,

    Affiliation: School of Biological Sciences, Bangor University, Bangor, Gwynedd, United Kingdom

    X
  • Antony M. Carr mail,

    a.m.carr@sussex.ac.uk

    Affiliation: Genome Damage and Stability Centre, University of Sussex, Brighton, Sussex, United Kingdom

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  • Valerie Garcia

    Affiliation: Genome Damage and Stability Centre, University of Sussex, Brighton, Sussex, United Kingdom

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  • Published: June 28, 2012
  • DOI: 10.1371/journal.pgen.1002801

About the Authors

Su-Jiun Lin, Christopher P. Wardlaw, Takashi Morishita, Izumi Miyabe, Antony M. Carr, Valerie Garcia
Genome Damage and Stability Centre, University of Sussex, Brighton, Sussex, United Kingdom
Charly Chahwan
Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada
Thomas Caspari, Ulrike Schmidt
School of Biological Sciences, Bangor University, Bangor, Gwynedd, United Kingdom

Corresponding Author

Email: a.m.carr@sussex.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AMC VG S-JL CPW. Performed the experiments: CPW S-JL VG TC US TM IM. Analyzed the data: AMC S-JL CPW CC VG IM. Contributed reagents/materials/analysis tools: TM. Wrote the paper: VG CPW AMC.