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Research Article

sox9b Is a Key Regulator of Pancreaticobiliary Ductal System Development

  • Marion Delous equal contributor mail,

    equal contributor Contributed equally to this work with: Marion Delous, Chunyue Yin

    marion.delous@ucsf.edu (MD); didier.stainier@ucsf.edu (DYRS)

    Affiliation: Department of Biochemistry and Biophysics, Program in Developmental and Stem Cell Biology, Liver Center and Diabetes Center, University of California San Francisco, San Francisco, California, United States of America

    X
  • Chunyue Yin equal contributor,

    equal contributor Contributed equally to this work with: Marion Delous, Chunyue Yin

    Affiliation: Department of Biochemistry and Biophysics, Program in Developmental and Stem Cell Biology, Liver Center and Diabetes Center, University of California San Francisco, San Francisco, California, United States of America

    X
  • Donghun Shin,

    Affiliation: Department of Biochemistry and Biophysics, Program in Developmental and Stem Cell Biology, Liver Center and Diabetes Center, University of California San Francisco, San Francisco, California, United States of America

    Current address: Department of Developmental Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

    X
  • Nikolay Ninov,

    Affiliation: Department of Biochemistry and Biophysics, Program in Developmental and Stem Cell Biology, Liver Center and Diabetes Center, University of California San Francisco, San Francisco, California, United States of America

    X
  • Juliana Debrito Carten,

    Affiliations: Department of Biology, Johns Hopkins University, Baltimore, Maryland, United States of America, Department of Embryology, The Carnegie Institution for Science, Baltimore, Maryland, United States of America

    X
  • Luyuan Pan,

    Affiliation: Howard Hughes Medical Institute and Division of Basic Science, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

    X
  • Taylur P. Ma,

    Affiliation: Howard Hughes Medical Institute and Division of Basic Science, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

    X
  • Steven A. Farber,

    Affiliations: Department of Biology, Johns Hopkins University, Baltimore, Maryland, United States of America, Department of Embryology, The Carnegie Institution for Science, Baltimore, Maryland, United States of America

    X
  • Cecilia B. Moens,

    Affiliation: Howard Hughes Medical Institute and Division of Basic Science, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

    X
  • Didier Y. R. Stainier mail

    marion.delous@ucsf.edu (MD); didier.stainier@ucsf.edu (DYRS)

    Affiliation: Department of Biochemistry and Biophysics, Program in Developmental and Stem Cell Biology, Liver Center and Diabetes Center, University of California San Francisco, San Francisco, California, United States of America

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  • Published: June 14, 2012
  • DOI: 10.1371/journal.pgen.1002754

About the Authors

Marion Delous, Chunyue Yin, Donghun Shin, Nikolay Ninov, Didier Y. R. Stainier
Department of Biochemistry and Biophysics, Program in Developmental and Stem Cell Biology, Liver Center and Diabetes Center, University of California San Francisco, San Francisco, California, United States of America
Juliana Debrito Carten, Steven A. Farber
Department of Biology, Johns Hopkins University, Baltimore, Maryland, United States of America
Juliana Debrito Carten, Steven A. Farber
Department of Embryology, The Carnegie Institution for Science, Baltimore, Maryland, United States of America
Luyuan Pan, Taylur P. Ma, Cecilia B. Moens
Howard Hughes Medical Institute and Division of Basic Science, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MD CY DYRS. Performed the experiments: MD CY DS LP TPM. Analyzed the data: MD CY DYRS. Contributed reagents/materials/analysis tools: NN JDC SAF CBM. Wrote the paper: MD CY DYRS. Commented on the manuscript: DS NN JDC SAF CBM.