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Research Article

TBC-8, a Putative RAB-2 GAP, Regulates Dense Core Vesicle Maturation in Caenorhabditis elegans

  • Mandy Hannemann,

    Affiliations: European Neuroscience Institute (ENI), Goettingen, Germany, International Max Planck Research School Molecular Biology, Goettingen, Germany

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  • Nikhil Sasidharan,

    Affiliations: European Neuroscience Institute (ENI), Goettingen, Germany, International Max Planck Research School Neuroscience, Goettingen, Germany

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  • Jan Hegermann,

    Affiliations: European Neuroscience Institute (ENI), Goettingen, Germany, DFG Research Center for Molecular Physiology of the Brain (CMPB), Goettingen, Germany

    Current address: Institute for Functional and Applied Anatomy, Hannover Medical School, Hannover, Germany

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  • Lena M. Kutscher,

    Affiliation: European Neuroscience Institute (ENI), Goettingen, Germany

    Current address: The Rockefeller University, New York, New York, United States of America

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  • Sabine Koenig,

    Affiliations: European Neuroscience Institute (ENI), Goettingen, Germany, DFG Research Center for Molecular Physiology of the Brain (CMPB), Goettingen, Germany

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  • Stefan Eimer mail

    seimer@gwdg.de

    Affiliations: European Neuroscience Institute (ENI), Goettingen, Germany, DFG Research Center for Molecular Physiology of the Brain (CMPB), Goettingen, Germany, Centre for Biological Signalling Studies (BIOSS), Albert-Ludwigs-Universitaet Freiburg, Freiburg, Germany

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  • Published: May 24, 2012
  • DOI: 10.1371/journal.pgen.1002722

About the Authors

Mandy Hannemann, Nikhil Sasidharan, Jan Hegermann, Lena M. Kutscher, Sabine Koenig, Stefan Eimer
European Neuroscience Institute (ENI), Goettingen, Germany
Mandy Hannemann
International Max Planck Research School Molecular Biology, Goettingen, Germany
Nikhil Sasidharan
International Max Planck Research School Neuroscience, Goettingen, Germany
Jan Hegermann, Sabine Koenig, Stefan Eimer
DFG Research Center for Molecular Physiology of the Brain (CMPB), Goettingen, Germany
Stefan Eimer
Centre for Biological Signalling Studies (BIOSS), Albert-Ludwigs-Universitaet Freiburg, Freiburg, Germany

Corresponding Author

Email: seimer@gwdg.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MH NS SE. Performed the experiments: MH JH LMK SK. Analyzed the data: MH JH SE. Wrote the paper: MH NS SE.