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Research Article

Histone H1 Depletion Impairs Embryonic Stem Cell Differentiation

  • Yunzhe Zhang equal contributor,

    equal contributor Contributed equally to this work with: Yunzhe Zhang, Marissa Cooke, Shiraj Panjwani

    Affiliations: School of Biology, Georgia Institute of Technology, Atlanta, Georgia, United States of America, The Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia, United States of America

    X
  • Marissa Cooke equal contributor,

    equal contributor Contributed equally to this work with: Yunzhe Zhang, Marissa Cooke, Shiraj Panjwani

    Affiliations: The Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia, United States of America, The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Georgia, United States of America

    X
  • Shiraj Panjwani equal contributor,

    equal contributor Contributed equally to this work with: Yunzhe Zhang, Marissa Cooke, Shiraj Panjwani

    Affiliations: School of Biology, Georgia Institute of Technology, Atlanta, Georgia, United States of America, The Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia, United States of America

    X
  • Kaixiang Cao,

    Affiliations: School of Biology, Georgia Institute of Technology, Atlanta, Georgia, United States of America, The Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia, United States of America

    X
  • Beth Krauth,

    Affiliation: The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Georgia, United States of America

    X
  • Po-Yi Ho,

    Affiliations: School of Biology, Georgia Institute of Technology, Atlanta, Georgia, United States of America, The Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia, United States of America

    X
  • Magdalena Medrzycki,

    Affiliations: School of Biology, Georgia Institute of Technology, Atlanta, Georgia, United States of America, The Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia, United States of America

    X
  • Dawit T. Berhe,

    Affiliation: The Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia, United States of America

    X
  • Chenyi Pan,

    Affiliations: School of Biology, Georgia Institute of Technology, Atlanta, Georgia, United States of America, The Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia, United States of America

    X
  • Todd C. McDevitt,

    Affiliations: The Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia, United States of America, The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Georgia, United States of America

    X
  • Yuhong Fan mail

    Yuhong.fan@biology.gatech.edu

    Affiliations: School of Biology, Georgia Institute of Technology, Atlanta, Georgia, United States of America, The Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia, United States of America

    X
  • Published: May 10, 2012
  • DOI: 10.1371/journal.pgen.1002691

About the Authors

Yunzhe Zhang, Shiraj Panjwani, Kaixiang Cao, Po-Yi Ho, Magdalena Medrzycki, Chenyi Pan, Yuhong Fan
School of Biology, Georgia Institute of Technology, Atlanta, Georgia, United States of America
Yunzhe Zhang, Marissa Cooke, Shiraj Panjwani, Kaixiang Cao, Po-Yi Ho, Magdalena Medrzycki, Dawit T. Berhe, Chenyi Pan, Todd C. McDevitt, Yuhong Fan
The Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia, United States of America
Marissa Cooke, Beth Krauth, Todd C. McDevitt
The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Georgia, United States of America

Corresponding Author

Email: Yuhong.fan@biology.gatech.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YF TCM. Performed the experiments: YZ MC SP KC BK P-YH MM DTB CP YF. Analyzed the data: YZ MC SP KC BK MM TCM YF. Contributed reagents/materials/analysis tools: YF TCM. Wrote the paper: YF TCM SP KC.