Advertisement
Research Article

Using Whole-Genome Sequence Data to Predict Quantitative Trait Phenotypes in Drosophila melanogaster

  • Ulrike Ober mail,

    uober@math.uni-goettingen.de

    Affiliation: Animal Breeding and Genetics Group, Georg-August-University Göttingen, Göttingen, Germany

    X
  • Julien F. Ayroles,

    Affiliations: Department of Genetics, North Carolina State University, Raleigh, North Carolina, United States of America, Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, United States of America

    X
  • Eric A. Stone,

    Affiliation: Department of Genetics, North Carolina State University, Raleigh, North Carolina, United States of America

    X
  • Stephen Richards,

    Affiliation: Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Dianhui Zhu,

    Affiliation: Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Richard A. Gibbs,

    Affiliation: Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Christian Stricker,

    Affiliation: agn Genetics GmbH, Davos, Switzerland

    X
  • Daniel Gianola,

    Affiliation: Department of Animal Sciences, University of Wisconsin–Madison, Wisconsin, United States of America

    X
  • Martin Schlather,

    Affiliation: Institute for Mathematics, University of Mannheim, Mannheim, Germany

    X
  • Trudy F. C. Mackay,

    Affiliation: Department of Genetics, North Carolina State University, Raleigh, North Carolina, United States of America

    X
  • Henner Simianer

    Affiliation: Animal Breeding and Genetics Group, Georg-August-University Göttingen, Göttingen, Germany

    X
  • Published: May 03, 2012
  • DOI: 10.1371/journal.pgen.1002685

About the Authors

Ulrike Ober, Henner Simianer
Animal Breeding and Genetics Group, Georg-August-University Göttingen, Göttingen, Germany
Julien F. Ayroles, Eric A. Stone, Trudy F. C. Mackay
Department of Genetics, North Carolina State University, Raleigh, North Carolina, United States of America
Julien F. Ayroles
Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, United States of America
Stephen Richards, Dianhui Zhu, Richard A. Gibbs
Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, United States of America
Christian Stricker
agn Genetics GmbH, Davos, Switzerland
Daniel Gianola
Department of Animal Sciences, University of Wisconsin–Madison, Wisconsin, United States of America
Martin Schlather
Institute for Mathematics, University of Mannheim, Mannheim, Germany

Corresponding Author

Email: uober@math.uni-goettingen.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: HS TFCM MS. Performed the experiments: RAG. Analyzed the data: UO. Contributed reagents/materials/analysis tools: UO JFA EAS CS MS TFCM. Wrote the paper: UO HS TFCM DG MS. Sequencing management: SR. DGRP sequencing bioinformatics: DZ. DGRP sequencing PI: RAG.