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Research Article

MicroRNA-277 Modulates the Neurodegeneration Caused by Fragile X Premutation rCGG Repeats

  • Huiping Tan,

    Affiliations: Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, United States of America, Division of Histology and Embryology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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  • Mickael Poidevin,

    Affiliation: Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, United States of America

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  • He Li,

    Affiliation: Division of Histology and Embryology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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  • Dahua Chen mail,

    chendh@ioz.ac.cn (DC); peng.jin@emory.edu (PJ)

    Affiliation: State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China

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  • Peng Jin mail

    chendh@ioz.ac.cn (DC); peng.jin@emory.edu (PJ)

    Affiliation: Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, United States of America

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  • Published: May 03, 2012
  • DOI: 10.1371/journal.pgen.1002681

About the Authors

Huiping Tan, Mickael Poidevin, Peng Jin
Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, United States of America
Huiping Tan, He Li
Division of Histology and Embryology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Dahua Chen
State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: PJ. Performed the experiments: HT MP. Analyzed the data: HT MP HL DC PJ. Contributed reagents/materials/analysis tools: HL DC PJ. Wrote the paper: HT PJ.