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Research Article

Progressive Telomere Dysfunction Causes Cytokinesis Failure and Leads to the Accumulation of Polyploid Cells

  • Judit Pampalona,
  • Cristina Frías,
  • Anna Genescà,
  • Laura Tusell mail

    laura.tusell@uab.es

    Affiliation: Department of Cell Biology, Physiology, and Immunology, Bioscience School, Universitat Autònoma de Barcelona, Bellaterra, Spain

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  • Published: April 26, 2012
  • DOI: 10.1371/journal.pgen.1002679

About the Authors

Laura Tusell
Department of Cell Biology, Physiology, and Immunology, Bioscience School, Universitat Autònoma de Barcelona, Bellaterra, Spain

Corresponding Author

Email: laura.tusell@uab.es

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LT AG. Performed the experiments: JP. Analyzed the data: LT JP. Wrote the paper: LT AG JP CF. Generated the HMEC-hTERT stable cell lines: CF.