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Research Article

The DSIF Subunits Spt4 and Spt5 Have Distinct Roles at Various Phases of Immunoglobulin Class Switch Recombination

  • Andre Stanlie,

    Affiliation: Department of Immunology and Genomic Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan

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  • Nasim A. Begum,

    Affiliation: Department of Immunology and Genomic Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan

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  • Hideo Akiyama,

    Affiliation: New Frontiers Research Laboratories, Toray Industries, Kanagawa, Japan

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  • Tasuku Honjo mail

    honjo@mfour.med.kyoto-u.ac.jp

    Affiliation: Department of Immunology and Genomic Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan

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  • Published: April 26, 2012
  • DOI: 10.1371/journal.pgen.1002675

About the Authors

Andre Stanlie, Nasim A. Begum, Tasuku Honjo
Department of Immunology and Genomic Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan
Hideo Akiyama
New Frontiers Research Laboratories, Toray Industries, Kanagawa, Japan

Corresponding Author

Email: honjo@mfour.med.kyoto-u.ac.jp

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AS NAB TH. Performed the experiments: AS NAB HA. Analyzed the data: AS NAB HA. Wrote the paper: AS NAB TH.