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Research Article

Patterns of Ancestry, Signatures of Natural Selection, and Genetic Association with Stature in Western African Pygmies

  • Joseph P. Jarvis,

    Affiliation: Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

    X
  • Laura B. Scheinfeldt equal contributor,

    equal contributor Contributed equally to this work with: Laura B. Scheinfeldt, Sameer Soi, Charla Lambert, Larsson Omberg

    Affiliation: Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

    X
  • Sameer Soi equal contributor,

    equal contributor Contributed equally to this work with: Laura B. Scheinfeldt, Sameer Soi, Charla Lambert, Larsson Omberg

    Affiliation: Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

    X
  • Charla Lambert equal contributor,

    equal contributor Contributed equally to this work with: Laura B. Scheinfeldt, Sameer Soi, Charla Lambert, Larsson Omberg

    Affiliation: Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

    X
  • Larsson Omberg equal contributor,

    equal contributor Contributed equally to this work with: Laura B. Scheinfeldt, Sameer Soi, Charla Lambert, Larsson Omberg

    Affiliation: Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America

    X
  • Bart Ferwerda,

    Affiliation: Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

    X
  • Alain Froment,

    Affiliation: UMR 208, IRD-MNHN, Musée de l'Homme, Paris, France

    X
  • Jean-Marie Bodo,

    Affiliation: Ministere de la Recherche Scientifique et de l'Innovation, Yaounde, Cameroon

    X
  • William Beggs,

    Affiliation: Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

    X
  • Gabriel Hoffman,

    Affiliation: Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America

    X
  • Jason Mezey,

    Affiliations: Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America, Department of Genetic Medicine, Weill Cornell Medical College, New York, New York, United States of America

    X
  • Sarah A. Tishkoff mail

    tishkoff@mail.med.upenn.edu

    Affiliations: Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

    X
  • Published: April 26, 2012
  • DOI: 10.1371/journal.pgen.1002641

About the Authors

Joseph P. Jarvis, Laura B. Scheinfeldt, Sameer Soi, Charla Lambert, Bart Ferwerda, William Beggs, Sarah A. Tishkoff
Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
Larsson Omberg, Gabriel Hoffman, Jason Mezey
Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America
Alain Froment
UMR 208, IRD-MNHN, Musée de l'Homme, Paris, France
Jean-Marie Bodo
Ministere de la Recherche Scientifique et de l'Innovation, Yaounde, Cameroon
Jason Mezey
Department of Genetic Medicine, Weill Cornell Medical College, New York, New York, United States of America
Sarah A. Tishkoff
Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Corresponding Author

Email: tishkoff@mail.med.upenn.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JPJ JM SAT. Performed the experiments: WB BF. Analyzed the data: JPJ LBS SS CL LO BF GH JM SAT. Contributed reagents/materials/analysis tools: AF J-MB GH LO JM. Wrote the paper: JPJ SAT.