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Research Article

A Genome-Wide Screen for Genetic Variants That Modify the Recruitment of REST to Its Target Genes

  • Rory Johnson,

    Affiliation: Stem Cell and Developmental Biology Group, Genome Institute of Singapore, Singapore, Singapore

    Current address: Bioinformatics and Genomics Group, Centre for Genomic Regulation (CRG) and UPF, Barcelona, Spain

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  • Nadine Richter,

    Affiliation: Stem Cell and Developmental Biology Group, Genome Institute of Singapore, Singapore, Singapore

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  • Gireesh K. Bogu,

    Affiliation: Stem Cell and Developmental Biology Group, Genome Institute of Singapore, Singapore, Singapore

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  • Akshay Bhinge,

    Affiliation: Stem Cell and Developmental Biology Group, Genome Institute of Singapore, Singapore, Singapore

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  • Siaw Wei Teng,

    Affiliation: Stem Cell and Developmental Biology Group, Genome Institute of Singapore, Singapore, Singapore

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  • Siew Hua Choo,

    Affiliation: Laboratory of Structural Biochemistry, Genome Institute of Singapore, Singapore, Singapore

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  • Lise O. Andrieux,

    Affiliation: Stem Cell and Developmental Biology Group, Genome Institute of Singapore, Singapore, Singapore

    Current address: Barcelona Supercomputing Center, Barcelona, Spain

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  • Cinzia de Benedictis,

    Affiliation: Bioinformatics and Genomics Group, Centre for Genomic Regulation (CRG) and UPF, Barcelona, Spain

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  • Ralf Jauch,

    Affiliation: Laboratory of Structural Biochemistry, Genome Institute of Singapore, Singapore, Singapore

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  • Lawrence W. Stanton mail

    stantonl@gis.a-star.edu.sg

    Affiliations: Stem Cell and Developmental Biology Group, Genome Institute of Singapore, Singapore, Singapore, Department of Biological Sciences, National University of Singapore, Singapore, Singapore

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  • Published: April 05, 2012
  • DOI: 10.1371/journal.pgen.1002624

About the Authors

Rory Johnson, Nadine Richter, Gireesh K. Bogu, Akshay Bhinge, Siaw Wei Teng, Lise O. Andrieux, Lawrence W. Stanton
Stem Cell and Developmental Biology Group, Genome Institute of Singapore, Singapore, Singapore
Siew Hua Choo, Ralf Jauch
Laboratory of Structural Biochemistry, Genome Institute of Singapore, Singapore, Singapore
Cinzia de Benedictis
Bioinformatics and Genomics Group, Centre for Genomic Regulation (CRG) and UPF, Barcelona, Spain
Lawrence W. Stanton
Department of Biological Sciences, National University of Singapore, Singapore, Singapore

Corresponding Author

Email: stantonl@gis.a-star.edu.sg

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: R Johnson, R Jauch, LW Stanton. Performed the experiments: N Richter, A Bhinge, SW Teng, SH Choo, LO Andrieux, C De Benedictis. Analyzed the data: R Johnson, GK Bogu, R Jauch. Wrote the paper: R Johnson, LW Stanton.