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Research Article

Statistical Analysis of Readthrough Levels for Nonsense Mutations in Mammalian Cells Reveals a Major Determinant of Response to Gentamicin

  • Célia Floquet,

    Affiliations: Université Paris-Sud, Institut de Génétique et Microbiologie, UMR8621, Orsay, France, CNRS, Orsay, France

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  • Isabelle Hatin,

    Affiliations: Université Paris-Sud, Institut de Génétique et Microbiologie, UMR8621, Orsay, France, CNRS, Orsay, France

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  • Jean-Pierre Rousset,

    Affiliations: Université Paris-Sud, Institut de Génétique et Microbiologie, UMR8621, Orsay, France, CNRS, Orsay, France

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  • Laure Bidou mail

    laure.bidou@igmors.u-psud.fr

    Affiliations: Université Paris-Sud, Institut de Génétique et Microbiologie, UMR8621, Orsay, France, CNRS, Orsay, France, UPMC Université Paris VI, Paris, France

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  • Published: March 29, 2012
  • DOI: 10.1371/journal.pgen.1002608

About the Authors

Célia Floquet, Isabelle Hatin, Jean-Pierre Rousset, Laure Bidou
Université Paris-Sud, Institut de Génétique et Microbiologie, UMR8621, Orsay, France
Célia Floquet, Isabelle Hatin, Jean-Pierre Rousset, Laure Bidou
CNRS, Orsay, France
Laure Bidou
UPMC Université Paris VI, Paris, France

Corresponding Author

Email: laure.bidou@igmors.u-psud.fr

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CF LB J-PR. Performed the experiments: CF LB. Analyzed the data: CF IH J-PR LB. Wrote the paper: CF IH J-PR LB.