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Research Article

Broad-Specificity mRNA–rRNA Complementarity in Efficient Protein Translation

  • Pamela A. Barendt,

    Affiliation: Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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  • Najaf A. Shah,

    Affiliation: Genomics and Computational Biology Graduate Group, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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  • Gregory A. Barendt,

    Affiliation: Perelman School of Medicine Information Services, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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  • Casim A. Sarkar mail

    casarkar@seas.upenn.edu

    Affiliations: Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Genomics and Computational Biology Graduate Group, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Department of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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  • Published: March 22, 2012
  • DOI: 10.1371/journal.pgen.1002598
  • Featured in PLOS Collections

About the Authors

Pamela A. Barendt, Casim A. Sarkar
Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
Najaf A. Shah, Casim A. Sarkar
Genomics and Computational Biology Graduate Group, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
Gregory A. Barendt
Perelman School of Medicine Information Services, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
Casim A. Sarkar
Department of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Corresponding Author

Email: casarkar@seas.upenn.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: PAB CAS. Performed the experiments: PAB. Analyzed the data: PAB NAS GAB CAS. Wrote the paper: PAB CAS.