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Research Article

A Systematic Analysis of Cell Cycle Regulators in Yeast Reveals That Most Factors Act Independently of Cell Size to Control Initiation of Division

  • Scott A. Hoose,

    Affiliation: Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America

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  • Jeremy A. Rawlings,

    Affiliation: Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America

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  • Michelle M. Kelly,

    Affiliation: Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America

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  • M. Camille Leitch,

    Affiliation: Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America

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  • Qotaiba O. Ababneh,

    Affiliation: Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America

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  • Juan P. Robles,

    Affiliation: Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America

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  • David Taylor,

    Affiliation: Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America

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  • Evelyn M. Hoover,

    Affiliation: Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America

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  • Bethel Hailu,

    Affiliation: Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America

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  • Kayla A. McEnery,

    Affiliation: Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America

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  • S. Sabina Downing,

    Affiliation: Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America

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  • Deepika Kaushal,

    Affiliation: Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America

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  • Yi Chen,

    Affiliation: Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America

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  • Alex Rife,

    Affiliation: Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America

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  • Kirtan A. Brahmbhatt,

    Affiliation: Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America

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  • Roger Smith III,

    Affiliation: Department of Veterinary Pathobiology, Texas A&M University, College Station, Texas, United States of America

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  • Michael Polymenis mail

    polymenis@tamu.edu

    Affiliation: Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America

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  • Published: March 15, 2012
  • DOI: 10.1371/journal.pgen.1002590

About the Authors

Scott A. Hoose, Jeremy A. Rawlings, Michelle M. Kelly, M. Camille Leitch, Qotaiba O. Ababneh, Juan P. Robles, David Taylor, Evelyn M. Hoover, Bethel Hailu, Kayla A. McEnery, S. Sabina Downing, Deepika Kaushal, Yi Chen, Alex Rife, Kirtan A. Brahmbhatt, Michael Polymenis
Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America
Roger Smith III
Department of Veterinary Pathobiology, Texas A&M University, College Station, Texas, United States of America

Corresponding Author

Email: polymenis@tamu.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MP. Performed the experiments: SAH JAR MMK MCL QOA JPR DT EMH BH KAM SSD DK YC AR KAB RS MP. Analyzed the data: SAH JAR MMK MCL QOA JPR DT EMH BH KAM SSD DK YC AR KAB RS MP. Contributed reagents/materials/analysis tools: SAH RS MP. Wrote the paper: SAH RS MP.