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Research Article

A Splice Site Variant in the Bovine RNF11 Gene Compromises Growth and Regulation of the Inflammatory Response

  • Arnaud Sartelet,

    Affiliation: Unit of Animal Genomics, GIGA-R and Department of Animal Sciences, Faculty of Veterinary Medicine, University of Liège, Liège, Belgium

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  • Tom Druet,

    Affiliation: Unit of Animal Genomics, GIGA-R and Department of Animal Sciences, Faculty of Veterinary Medicine, University of Liège, Liège, Belgium

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  • Charles Michaux,

    Affiliation: Unit of Bioinformatics, Department of Animal Sciences, Faculty of Veterinary Medicine, University of Liège, Liège, Belgium

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  • Corinne Fasquelle,

    Affiliation: Unit of Animal Genomics, GIGA-R and Department of Animal Sciences, Faculty of Veterinary Medicine, University of Liège, Liège, Belgium

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  • Sarah Géron,

    Affiliation: Unit of Animal Genomics, GIGA-R and Department of Animal Sciences, Faculty of Veterinary Medicine, University of Liège, Liège, Belgium

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  • Nico Tamma,

    Affiliation: Unit of Animal Genomics, GIGA-R and Department of Animal Sciences, Faculty of Veterinary Medicine, University of Liège, Liège, Belgium

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  • Zhiyan Zhang,

    Affiliation: Unit of Animal Genomics, GIGA-R and Department of Animal Sciences, Faculty of Veterinary Medicine, University of Liège, Liège, Belgium

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  • Wouter Coppieters,

    Affiliation: Unit of Animal Genomics, GIGA-R and Department of Animal Sciences, Faculty of Veterinary Medicine, University of Liège, Liège, Belgium

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  • Michel Georges,

    Affiliation: Unit of Animal Genomics, GIGA-R and Department of Animal Sciences, Faculty of Veterinary Medicine, University of Liège, Liège, Belgium

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  • Carole Charlier mail

    carole.charlier@ulg.ac.be

    Affiliation: Unit of Animal Genomics, GIGA-R and Department of Animal Sciences, Faculty of Veterinary Medicine, University of Liège, Liège, Belgium

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  • Published: March 15, 2012
  • DOI: 10.1371/journal.pgen.1002581

About the Authors

Arnaud Sartelet, Tom Druet, Corinne Fasquelle, Sarah Géron, Nico Tamma, Zhiyan Zhang, Wouter Coppieters, Michel Georges, Carole Charlier
Unit of Animal Genomics, GIGA-R and Department of Animal Sciences, Faculty of Veterinary Medicine, University of Liège, Liège, Belgium
Charles Michaux
Unit of Bioinformatics, Department of Animal Sciences, Faculty of Veterinary Medicine, University of Liège, Liège, Belgium

Corresponding Author

Email: carole.charlier@ulg.ac.be

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MG CC. Performed the experiments: AS CF SG NT. Analyzed the data: AS TD CM ZZ MG CC. Contributed reagents/materials/analysis tools: TD WC. Wrote the paper: AS MG CC.