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Research Article

Genetic Architecture of Highly Complex Chemical Resistance Traits across Four Yeast Strains

  • Ian M. Ehrenreich mail,

    Ian.Ehrenreich@usc.edu (IME); leonid@genomics.princeton.edu (LK)

    Affiliations: Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America, Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, United States of America, Howard Hughes Medical Institute, Princeton University, Princeton, New Jersey, United States of America, Molecular and Computational Biology Section, University of Southern California, Los Angeles, California, United States of America

    X
  • Joshua Bloom equal contributor,

    equal contributor Contributed equally to this work with: Joshua Bloom, Noorossadat Torabi, Xin Wang

    Affiliations: Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America, Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America

    X
  • Noorossadat Torabi equal contributor,

    equal contributor Contributed equally to this work with: Joshua Bloom, Noorossadat Torabi, Xin Wang

    Affiliations: Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America, Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America

    X
  • Xin Wang equal contributor,

    equal contributor Contributed equally to this work with: Joshua Bloom, Noorossadat Torabi, Xin Wang

    Affiliations: Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America, Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America

    X
  • Yue Jia,

    Affiliations: Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America, Howard Hughes Medical Institute, Princeton University, Princeton, New Jersey, United States of America

    X
  • Leonid Kruglyak mail

    Ian.Ehrenreich@usc.edu (IME); leonid@genomics.princeton.edu (LK)

    Affiliations: Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America, Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, United States of America, Howard Hughes Medical Institute, Princeton University, Princeton, New Jersey, United States of America

    X
  • Published: March 15, 2012
  • DOI: 10.1371/journal.pgen.1002570

About the Authors

Ian M. Ehrenreich, Joshua Bloom, Noorossadat Torabi, Xin Wang, Yue Jia, Leonid Kruglyak
Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America
Ian M. Ehrenreich, Leonid Kruglyak
Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, United States of America
Ian M. Ehrenreich, Yue Jia, Leonid Kruglyak
Howard Hughes Medical Institute, Princeton University, Princeton, New Jersey, United States of America
Ian M. Ehrenreich
Molecular and Computational Biology Section, University of Southern California, Los Angeles, California, United States of America
Joshua Bloom, Noorossadat Torabi, Xin Wang
Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: IME LK. Performed the experiments: IME NT XW. Analyzed the data: IME JB. Wrote the paper: IME LK. Constructed strains: IME XW YJ. Designed microarrays: IME.